Precision Medicine for more Oxygen - COVID-19 extensio

Completed

Conditions: corona
COVID19
10047438
10024970

Registration Number: NL-OMON52166

Lead Sponsor: Academisch Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 130

Inclusion Criteria

for Patients:
-Age: 40-65 years
-Proven ex-COVID-19: Hospitalised: Positive PCR / serology for SARS-CoV2 or
CORADS score 4/5, Non-hospitalised: Positive PCR / serology for SARS-CoV2.
-Able to provide informed consent
-Access to internet (either at home or via relatives/friends).
-Understanding of Dutch language

for healthy volunteers:
- age 18-65
- For the recovered healthy volunteers: proven ex-COVID-19: with a positive PCR
/ serology for SARS-CoV2Able to provide informed consent
- Understanding of Dutch language

Exclusion Criteria

-Inability to provide informed consent
-History or suspicion of inability to cooperate adequately
-Participation in any other study involving investigational or marketed
products concomitantly or within four weeks prior to entry into the study or
during the study;
-Investigator*s uncertainty about the willingness or ability of the patient to
comply with the protocol requirements
-Patients with terminal illness;

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>A) Lung damage assessed by CT scans at approximately t = 3-6 months and t =<br /><br>12-18 months after SARS-COV2 infection and the association of this damage with<br /><br>biomarkers and the exposome.<br /><br>B) Difference in EQ-5D Index Score between intervention and control groups at t<br /><br>= 12 months after SARS-COV2 infection.</p><br>

Secondary Outcome Measures