NCT02306980已完成不适用
Oral Administration of Colostrum to Premature Babies: Impact on the Oral Microbiota
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- Oral microbiota
研究概览
简要总结
Oropharyngeal administration of mother's colostrum to premature infants has been proposed as a stimulus to the oropharyngeal lymphatic tissues to decrease the incidence of pneumonia and sepsis, particularly in intubated babies. We propose to study the impact of this intervention on the composition of the oral microbiota.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 12 Hours 至 7 Days(Child)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •premature infant with birth weight < 1500
- •intubated in the first 48 hours of life
- •available maternal colostrum
排除标准
- •lethal condition
研究组 & 干预措施
Colostrum
Experimental
Colostrum administration
干预措施: Colostrum (Other)
Control
No Intervention
Routine care
结局指标
主要结局
Oral microbiota
时间窗: Difference between enrollment, 48 hours and 96 hours
Changes in the composition of the community of microbes inhabiting the oral-cavity after administration of oropharyngeal maternal colostrum.
次要结局
未报告次要终点
研究者
研究点 (2)
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