NCT02306980
Completed
Not Applicable
Oral Administration of Colostrum to Premature Babies: Impact on the Oral Microbiota
ConditionsChanges in the Oral Microbiota
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Changes in the Oral Microbiota
- Sponsor
- University of California, Davis
- Enrollment
- 12
- Locations
- 1
- Primary Endpoint
- Oral microbiota
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
Oropharyngeal administration of mother's colostrum to premature infants has been proposed as a stimulus to the oropharyngeal lymphatic tissues to decrease the incidence of pneumonia and sepsis, particularly in intubated babies. We propose to study the impact of this intervention on the composition of the oral microbiota.
Investigators
Eligibility Criteria
Inclusion Criteria
- •premature infant with birth weight \< 1500
- •intubated in the first 48 hours of life
- •available maternal colostrum
Exclusion Criteria
- •lethal condition
Outcomes
Primary Outcomes
Oral microbiota
Time Frame: Difference between enrollment, 48 hours and 96 hours
Changes in the composition of the community of microbes inhabiting the oral-cavity after administration of oropharyngeal maternal colostrum.
Study Sites (1)
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