Oral Administration of Colostrum to Premature Babies: Impact on the Oral Microbiota
- Conditions
- Changes in the Oral Microbiota
- Registration Number
- NCT02306980
- Lead Sponsor
- University of California, Davis
- Brief Summary
Oropharyngeal administration of mother's colostrum to premature infants has been proposed as a stimulus to the oropharyngeal lymphatic tissues to decrease the incidence of pneumonia and sepsis, particularly in intubated babies. We propose to study the impact of this intervention on the composition of the oral microbiota.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 12
- premature infant with birth weight < 1500
- intubated in the first 48 hours of life
- available maternal colostrum
- lethal condition
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Oral microbiota Difference between enrollment, 48 hours and 96 hours Changes in the composition of the community of microbes inhabiting the oral-cavity after administration of oropharyngeal maternal colostrum.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
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Trial Locations
- Locations (1)
UC Davis Children's Hospital
🇺🇸Sacramento, California, United States
UC Davis Children's Hospital🇺🇸Sacramento, California, United States