Optical coherence tomography angiography findings in patients with acute non-arteritic central retinal artery occlusion treated with carbogen inhalatio
Active, not recruiting
- Conditions
- on-arteritis central retinal artery occlusionCentral retinal artery occlusionOptical coherence tomography angiographyCarbogen
- Registration Number
- TCTR20210510007
- Lead Sponsor
- /A
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- All
- Target Recruitment
- 28
Inclusion Criteria
Patients with acute (within 7 days from onset) non-arteritic central retinal artery occlusion presented at Songklanagarind hospital from 1 January 2021 to 31 June 2022
Exclusion Criteria
1.Patients with acute ocular comorbidity warranting other acute management i.e., giant cell arteritis receiving IV steroid or combined with central retinal vein occlusion
2.Patients previously treated with carbogen inhalation
3.Unable to perform OCTA due to in-cooperation, dense cataract, unable to sit upright etc.
4.Pregnancy of any trimester
5.Chronic obstructive pulmonary disease
6.Patients under going any other clinical trials
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Vessel density Before, 12-24 hours, 36-48 hours, 1-2 weeks, 4-6 weeks after carbogen inhalation Optical coherent tomography angiography,Flow area Before, 12-24 hours, 36-48 hours, 1-2 weeks, 4-6 weeks after carbogen inhalation Optical coherent tomography angiography,Foveal vessel density Before, 12-24 hours, 36-48 hours, 1-2 weeks, 4-6 weeks after carbogen inhalation Optical coherent tomography angiography,Central macular thickness Before, 12-24 hours, 36-48 hours, 1-2 weeks, 4-6 weeks after carbogen inhalation Optical tomography angiography
- Secondary Outcome Measures
Name Time Method Visual acuity Before, 12-24 hours, 36-48 hours, 1-2 weeks, 4-6 weeks after carbogen inhalation Snellen chart