Comparison of Pregabalin and Cinnarizine on treatment of children with migraine
Phase 3
- Conditions
- Migraine.Migraine
- Registration Number
- IRCT20230415057911N1
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 74
Inclusion Criteria
Consent of parents and children over 13 years to participate in the study
Boys and girls aged 6 to 17 years with migraine prophylaxis
Migraine diagnosis based on the criteria of the International Headache Society, which includes cases of migraine without aura (5 attacks), migraine with aura (2 attacks), and each attack lasts 1 to 72 hours, and it is pulsating and severe, and accompanied by symptoms With nausea or vomiting, photophobia, phonophobia
Not taking pregabalin and cinnarizine in the past
Exclusion Criteria
Drug Intolerance (symptoms such as diarrhea, nausea and vomiting)
anaphylaxis
severe dizziness
excessive sleepiness
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Frequency of migraine headaches. Timepoint: The beginning of the study, 4, 8 and 12 weeks after the intervention. Method of measurement: Patient's history and notes.
- Secondary Outcome Measures
Name Time Method Severity of migraine headaches. Timepoint: The beginning of the study, 4, 8 and 12 weeks after the intervention. Method of measurement: Based on the Visual Analogue Scale (VAS).;The rate of migraine attacks disability. Timepoint: The beginning of the study, 4, 8 and 12 weeks after the intervention. Method of measurement: Based on Pediatric Migraine Disability Assessment (PedMIDAS) tool.