Initial CT Findings and CO-RADS Stage in COVID-19

Completed

• Conditions: SARS-CoV Infection; Pneumonia, Viral; Covid19

• Registration Number: NCT04789447
• Lead Sponsor: Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey

Brief Summary

This study aims to determine whether patients with different real-time reverse transcriptase-polymerase chain reaction (PCR), chest computed tomography (CT) and laboratory findings have different clinical outcomes.

Detailed Description

This study aims to determine the rates of PCR positivity and CT findings in hospitalized patients with a diagnosis of COVID-19, to determine whether there is a difference in mortality and need for ICU between patients grouped according to the PCR positivity and presence of CT findings, and to evaluate the effect of the CO-RADS stage on these outcomes. Moreover, it is to compare the effects of inflammation and coagulation markers and CO-RADS stage on the severity of the disease

Study Timeline

• Study Start: 2021-03-04
• Study First Submitted: 2021-03-04
• Study First Submitted QC: 2021-03-08
• Study First Posted: 2021-03-09
• Primary Completion: 2021-05-06
• Study Completion: 2021-05-06
• Status Verified: 2021-06
• Last Update Submitted: 2021-06-04
• Last Update Posted: 2021-06-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 895

Inclusion Criteria

• Aged 18 years and over,
• Having SARS-CoV-2 RT-PCR test and chest CT examinations performed at the time of application or within 24 hours after admission
• RT-PCR positivity in nasopharyngeal swabs sample, and/or the presence of clinical and laboratory findings of SARS-CoV-2 infection and/or the presence of COVID-19-compatible radiological findings in chest CT, and being diagnosed with COVID-19

Exclusion Criteria

• Patients with negative SARS-CoV-2 PCR test, pneumonia on CT but not given Covid-19 treatment by not considering Covid-19 by their doctor will not be included.
• Patients whose data are not available
• Patients with poor CT image quality
• Patients who were transferred to another hospital

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
mortality	up to 30 days	mortality during hospitalization and within 14 days after hospitalization

Secondary Outcome Measures

Name	Time	Method
need for intensive care	up to 30 days	need for intensive care during hospitalization and within 30 days after hospitalization
need for intenvasive mechanical ventilation	up to 30 days	need for intenvasive mechanical ventilation during hospitalization and within 30 days after hospitalization

Trial Locations

Locations (1)

Sultan Abdülhamid Han Training and Research Hospital; 🇹🇷 Istanbul, Turkey