跳至主要内容
临床试验/CTRI/2025/01/079418
CTRI/2025/01/079418招募中3 期

Evaluation of Efficacy of Chamomilla With Babul Gum Paint In Comparison With Chlorhexidine Gluconate Gum Paint On Periodontal Health Status A Clinico Microbiological Study

Dr Ankita Gadekar1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年2月3日最近更新:

试验速览

阶段
3 期
状态
招募中
发起方
入组人数
60
试验地点
1
主要终点
To evaluate the efficacy of chamomilla with babul gum paint on periodontal health status

研究概览

简要总结

EVALUATION OF EFFICACY OF CHAMOMILLA WITH BABUL GUMPAINT IN COMPARISON WITH CHLORHEXIDINE GLUCONATE GUMPAINT ON PERIODONTAL HEALTH STATUS: A CLINICO‑MICROBIOLOGICAL STUDY

 Abstract: Gingivitis and Periodontitis are a multifactorial inflammatory disease of the oral cavity that results in alveolar bone destruction and is main reason for tooth loss. Gum paint provide a safe and effective chemical means of reducing or eliminating bacteria and relieving infection of oral tissue. Herbs and plant-derived products have a long history of safe use as natural products in the treatment of various diseases. The primary objective of study is to evaluate and compare the efficacy of chamomilla with babul gum paint and chlorhexidine gluconate gum paint on periodontal health status. It is randomised clinical trial study with 60 adult patient having mild to moderate gingivitis and periodontitis. They were divided into 2 groups each with 30 patients. Group A were given Herbal gumpaint and Group B given conventional gumpaint. All participants were brought to baseline. Indices were taken at baseline, 7 days, 14 days and 21 days. MIC (Minimal Inhibitory Concentration) and zone of inhibition was checked both Streptococcus mutans, Lactobacillus, Prophyromonas Gingivalis,, Tannerella  forsythia, Prevotella Intermedia . Gingival crevicular fluid (GCF) were taken at baseline and after 21 days to check Colony forming unit (CFU) of the samples. Data will be analyzed using SPSS software v23. The level of significance will be kept at 5%. Data will be tested for normality using the Shapiro-Wilk test. Intragroup comparison of the variables will be done using either repeated measures ANOVA test or Friedman two-way ANOVA test followed by Bonferroni test for pairwise comparisons. Intergroup comparison of the variables at each interval will be done using either the independent t test or the mann whitney test.

研究设计

研究类型
Interventional
分配方式
Other
盲法
Participant Blinded

入排标准

年龄范围
30.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • Patients with mild to moderate gingivitis and periodontitis.

排除标准

  • Patient with major systemic disease Patient not willing to participate in study.

结局指标

主要结局

To evaluate the efficacy of chamomilla with babul gum paint on periodontal health status

时间窗: Baseline 7 days 14 days and 21 days

次要结局

  • To evaluate and compare the Zone of inhibition of Herbal and Chlorhexidine Gum paint on Streptococcus Mutans Lactobacillus Prophyromonas Gingivalis Tannerella forsythia Prevotella Intermedia(Before and after use of gum paint)

研究者

发起方
Dr Ankita Gadekar
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Ankita Vinayak Gadekar

JMFs A.C.P.M Dental College

研究点 (1)

Loading locations...

相似试验