IRCT20240706062343N1尚未招募3 期
Evaluating the effect of timing of administration of the drugs atomoxetine and trazodone in divided doses on the number of apneic episodes and sleep indexes in obstructive sleep apnea patients
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 入组人数
- 18
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 21 years 至 65 years（—）
- 性别
- All
入选标准
- •Patients with a diagnosis of obstructive sleep apnea in medical records with AHI=20 in latest polysomnography (if performed)
- •Patients who are not candidates for or aren't compliant with standard obstructive sleep apnea treatments
排除标准
- •Presence of other diseases (except for controlled hypertension, hyperlipidemia, diabetes)
- •Usage of any drug that interferes with respiratory physiology, sleep/wake and muscles, including methocarbamol, tramadol, TCAs, SSRIs, SNRIs, respiratory stimulants of depressants, hypnotics, central nervous system stimulants, central sleep apnea, etc
- •Claustrophobia
- •Hypersensitivity to lidocaine, atomoxetine or trazodone
- •Presence of underlying cardiac disease including arrhythmia
- •Usage of psychiatric drugs (including atomoxetine) or any drug that is required for medical treatment and cannot be skipped on the night of the study
- •In females: pregnancy
- •History of seizure, panic disorder, hyperventilation syndrome, attention deficient hyperactivity disorder, autism spectrum disorder
研究者
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