A prospective study to assess the screening value of N-terminal pro-B-type natriuretic peptide (NT-proBNP) for the identification of patients that benefit from additional cardiac testing prior to vascular surgery.
Recruiting
- Conditions
- on-cardiac surgery, NT-proBNP, Perioperative cardiac complications
- Registration Number
- NL-OMON27132
- Lead Sponsor
- Erasmus Medical Center, Department of Anesthesiology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 1800
Inclusion Criteria
1. Patients with peripheral vascular atherosclerosis scheduled for vascular surgery involving either:
a. revascularization utilizing aortic or proximal lower extremity procedures, or
b. distal lower extremity vascular reconstruction, are eligible to participate.
Exclusion Criteria
1. Emergency surgical procedures;
2. Unability or unwillingness to provide written informed consent;
3. Previous participation in this same trial; 4. Concurrent participation in another clinical trial;
5. Contraindication for cardiac stress testing.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary objective of this trial is to validate the screening potential of NT-proBNP in a population of low to intermediate risk patients, i.e. patients with zero to two cardiac risk factors, scheduled for vascular surgery.
- Secondary Outcome Measures
Name Time Method The secondary objective is to identify prior to vascular surgery high risk patients, with three or more cardiac risk factors, with a normal stress test..