Surveillance for nasopharyungeal carriage of S.pneumoniae in young children of Okinawa.

Not Applicable

Recruiting

• Conditions: asopharyngeal carriage of S.pneumoniae.

• Registration Number: JPRN-UMIN000006988
• Lead Sponsor: Hideki Akeda

Brief Summary

Result of surveillance of nasopharyngeal carriage in 2012 was published in 2015 (World Journal Of Vaccine 2015,5,88-95). Abstract:PCV7 was subsidized by the national funding system from 2011.After that PCV7 were immunized universally. Carriage rate of S.pneumoniae in healthy 2 to 24 month old children was 24.8% (180/725). Carriage of PCV7 serotypes accounted for 21.8%. The result of multivariate data analysis showed that the pneumococcal carriage rate of non-PCV7 serotypes was significantly high in infant with sibling and daycare attendance.On the other hand, carriage rate of PCV7 serotypes had only significantly high risk in infant with siblings and did not have a risk dependent on daycare attendance. The result demonstrates that PCV7 vaccination decrease the overall nasopharyngeal carriage of PCV7 serotypes in vaccinated children including children at risk such as attending daycare.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-01-05
• Study Completion: 2017-03-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 1600

Inclusion Criteria

Not provided

Exclusion Criteria

None

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serotyping of S.pneumoniae from nasopharyngeal carriage of healthy young children.

Secondary Outcome Measures

Name	Time	Method
Risk factor analysis of nasopharyngeal carriage : sibling,childcare attendance.