临床试验/NCT06711653

NCT06711653已完成不适用

Development of Bone-vestibular Evoked Myogenic Potential

Taipei City Hospital1 个研究点分布在 1 个国家目标入组 20 人开始时间: 2022年11月7日最近更新: 2024年12月2日

适应症

干预措施

试验速览

阶段: 不适用
状态: 已完成
发起方: Taipei City Hospital
入组人数: 20
试验地点: 1
主要终点: Vemp response rate

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

This study aims to evaluate the effects of different masking conditions on cervical vestibular evoked myogenic potential (cVEMP) responses. Vertical-axis vibrations (VAVs) of 500-Hz short-tone bursts (STB500) and 750-Hz short-tone bursts (STB750) were used to elicit cVEMP responses. These stimuli were delivered through a Mini-Shaker placed at the vertex (Cz) under three masking conditions: no masking (NOM), speech noise masking (SNM), and random interstimulus-interval tone bursts (rISITB). The study focused on testing protocols that can potentially improve unilateral VEMP testing and explore its clinical applicability.

详细描述

Participants and Ethics:

The study recruited 20 healthy adults (10 males and 10 females, aged 20-37 years), all of whom had normal otoscopic findings and no history of hearing issues. Ethical approval was obtained, and all participants provided informed consent.

Bone Conduction Vibrations (BCV):

Bone-conducted vibrations were generated using a SmartEP system and delivered via a Mini-Shaker transducer. Stimuli included 500 Hz and 750 Hz short-tone bursts (STB500 and STB750), calibrated to appropriate levels, with specific rise, plateau, and fall times.

Masking Conditions:

研究设计

研究类型: Interventional
分配方式: Na
干预模型: Single Group
主要目的: Basic Science
盲法: None

入排标准

年龄范围: 20 Years 至 40 Years（Adult）
性别: All
接受健康志愿者: 是

入选标准

•20y-40y adult

排除标准

•Having history of hearing loss or dizziness
•failed hearing screening test
•Having history of head or neck surgery

研究组 & 干预措施

Different Test Conditions

Experimental

one test group with different test conditions

干预措施: Vestibular evoke myogenic potential (Diagnostic Test)

结局指标

主要结局

Vemp response rate

时间窗: up to 24 weeks

This study investigates VEMP response rates under different frequencies (500 Hz, 750 Hz) and masking conditions (no masking, speech noise, random tone bursts) to evaluate the effects of masking on VEMP responses.

次要结局

未报告次要终点

研究者

发起方

Taipei City Hospital

申办方类型

Other Gov

责任方

Sponsor

研究点 (1)

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