Functional Imaging in the Acute Phase of Transient Ischemic Attacks
- Conditions
- Transient Ischemic Attack
- Interventions
- Diagnostic Test: Functional Magnetic Resonance Imaging
- Registration Number
- NCT03928977
- Lead Sponsor
- Centre Hospitalier Universitaire de Besancon
- Brief Summary
The aim of the study is to find a radiological biomarker of Transient Ischemic Attacks (TIA) thanks to functional Magnetic Resonance Imaging (fMRI) done within the 24 hour after symptoms onset.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 70
- Patient admitted in for a transient neurologic deficit and suspicion of TIA of carotid circulation
- Prescription for conventionnal MRI
- Contraindication to MRI
- Previous neurological disease (with lesions)
- Severe psychiatric disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Confirmed non-TIA Functional Magnetic Resonance Imaging Not-confirmed TIA at 3 months with standardized neurological expertise Confirmed TIA Functional Magnetic Resonance Imaging Confirmed TIA at 3 months with standardized neurological expertise
- Primary Outcome Measures
Name Time Method Blood-Oxygen-Level Dependent signal 24 hours after symptoms onset BOLD effect differences in motor cortex from pathological side versus healthy side measured by fMRI within the 24 hours after symptom onset, during a motor paradigm
- Secondary Outcome Measures
Name Time Method Resting state 24 hours after symptoms onset Bold effect differences in resting state networks from pathological side versus healthy side measured by fMRI within the 24 hours after symptom onset, during a motor paradigm
Trial Locations
- Locations (1)
CHU de Besançon
🇫🇷Besançon, France