Development of Bone Grafts Using Adipose Derived Stem Cells and Different Scaffolds

Completed

• Conditions: Overweight
• Interventions: Procedure: Cell Culture

• Registration Number: NCT01218945
• Lead Sponsor: University of Zurich

Brief Summary

The repair of large osseous defects remains still unsolved. Aim of this study is to isolate and cultivate fat-derived progenitor cells and differentiation into osteoblasts. Therefore, our research idea is to pre-engineer large synthetic bone grafts and study the vascularization process in vivo.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-11
• Study First Submitted: 2010-09-29
• Study First Submitted QC: 2010-10-08
• Study First Posted: 2010-10-11
• Primary Completion: 2012-12
• Study Completion: 2012-12
• Status Verified: 2013-06
• Last Update Submitted: 2013-06-18
• Last Update Posted: 2013-06-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 33

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Fat Removal	Cell Culture	Patients undergoing surgical fat removal

Trial Locations

Locations (1)

University Hospital Zurich, Clinic of Reconstructive Surgery; 🇨🇭 Zurich, ZH, Switzerland