Effects of Low Dose ketamıne on Postpartum Depression During Caesarean Sections
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- postpartum depression
研究概览
简要总结
The results of ketamine, ketamine and midazolom and placebo can be copied after birth in cesareans subjected to spinal anesthesia.
详细描述
Postpartum depression will be evaluated by dividing the patients into 3 groups: group 1 as ketamine, group 2 as ketamine and midasom, and group 3 as placebo group.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •American Society of Anesthesiologists 2-.3 18 -45years old Patients planned to be born by cesarean section The patient requests a cesarean section with spinal anesthesia
- •ExclusionCriteria:
- •Pathological obstetric complications
- •Hypertension
- •Contraindication for ketamine Contraindication for spinal
排除标准
- 未提供
研究组 & 干预措施
Grup 1 -Ketamine Group
Ketamine Group (GROUP 1) 0.5 mg/kg IV single dose bolus diluted to 5 ml with 0.9% saline
干预措施: Application of ketamine and midazolam or ketamine alone to patients undergoing cesarean section under spinal anesthesia (Drug)
Group 2-ketamine + midazolam
Midazolam 0.0125 mg/kg is given followed by a single IV bolus dose of 0.5 mg/kg diluted to 5 ml with 0.9% saline.
干预措施: Application of ketamine and midazolam or ketamine alone to patients undergoing cesarean section under spinal anesthesia (Drug)
Group 3-placebo
Group 3-placebo ;A single dose of IV 5 ml physiological saline will be given.
干预措施: Application of ketamine and midazolam or ketamine alone to patients undergoing cesarean section under spinal anesthesia (Drug)
结局指标
主要结局
postpartum depression
时间窗: 4 weeks
Reducing postpartum depression with low-dose ketamine
intraoperative complications
时间窗: 1 day
Reducing postpartum depression by reducing ketamine-related intraoperative complications
postoperative pain
时间窗: 1 day
Reducing postoperative pain with low dose ketamine
次要结局
未报告次要终点
研究者
DUYGU DEMİROZ
principal investigator
Inonu University