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Clinical Trials/NCT07354113
NCT07354113
Not yet recruiting
Not Applicable

Feasibility and Acceptability of Peer Intervention for Improving Mental Health Among People Accessing Hormone Care

University of Michigan1 site in 1 country100 target enrollmentStarted: March 1, 2026Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
100
Locations
1
Primary Endpoint
Feasibility assessed by Acceptability based on the average total Abbreviated Acceptability Rating Profile (AARP) score at 6 months

Overview

Brief Summary

The purpose of this study is to test whether the peer support program is acceptable, possible, and can improve mental health among individuals accessing hormone care. Eligible participants will be enrolled and randomized to the support program or enhanced usual care arm. Participants will take part in this study for 6 months.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Patients with hormone condition aged 18 years or older and English speaking
  • Initiating or receiving hormone care in Michigan
  • Report mild depression or anxiety symptoms, as determined by:
  • A Patient Health Questionnaire (PHQ9) score ≥ 5 AND/OR
  • A Generalized Anxiety Disorder (GAD) score ≥
  • Interest or willingness to participate in peer support group meetings either in-person or virtually

Exclusion Criteria

  • Unable to provide informed consent for any reason
  • Not fluent in English
  • Determination by patient's attending healthcare provider that peer mentorship is not appropriate due to unstable psychosis, cognitive disorder, or severe personality disorder, or other issue
  • At imminent risk of suicide, as determined by active suicide ideation with intent and/or a specific plan (endorsed Columbia Suicide Severity Rating Scale number 4 or number 5 in the past month, number 6 in the past 3 months, or spontaneous report)
  • Already receiving or intending to receive formalized individual peer specialist services through another community mental health program or organization
  • Residing outside of the state of Michigan, or planning to move out of the state of Michigan in the next 6 months

Arms & Interventions

Peer support group

Experimental

Participants in the peer support group will be contacted by the peer coordinator to be connected with a peer mentor and will have access to peer support options, namely, one-one one meetings with a peer mentor, group meetings with mentors and other participants, and medical appointment buddy.

Intervention: Peer support group (Behavioral)

Enhanced Usual Care (EUC)

Other

EUC Documents will be disseminated with hormone care information and resources to share with patients relevant to the participants specific hormone condition or type of hormone care.

Intervention: Enhanced Usual Care (EUC) (Other)

Outcomes

Primary Outcomes

Feasibility assessed by Acceptability based on the average total Abbreviated Acceptability Rating Profile (AARP) score at 6 months

Time Frame: 6 months

The 9-item AARP is adapted to specifically address this peer support intervention for individuals seeking hormone care. Participants will respond to a 6-point Likert scale rating participants agreement with each acceptability statement. Total scores range from 9-54 with a higher score indicating greater acceptability.

Feasibility based on the number of participants that agreed to participate on the study out of total number of individuals approached for study participation.

Time Frame: Up to 6 months (recruitment period)

Feasibility assessed by Practicality based on the total number of one-on-one in-person sessions vs one-on-one virtual sessions

Time Frame: 6 months

This is defined as the total number of one-on-one in-person sessions vs one-on-one virtual sessions.

Feasibility assessed by Practicality based on the total the number participants engaged with group sessions in-person vs. number of participants engaged virtually

Time Frame: 6 months

This is defined as the total number of participants engaged with group sessions in-person vs. number of participants engaged virtually.

Safety based on the number of related adverse events

Time Frame: 6 months

Related events included will be definitely, probably, and possibly related events (defined per protocol). The grading scale that will be used for these events include: 1. \- Mild adverse event (AE) - No treatment needed 2. \- Moderate AE - Resolved with treatment 3. \- Severe AE - Inability to carry on normal activities, required professional medical attention 4. \- Life-threatening or disabling AE 5. \- Fatal AE

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Daphna Stroumsa

Assistant Professor of Obstetrics and Gynecology

University of Michigan

Study Sites (1)

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