Clinical and Paraclinical Characteristics of Severe Bronchiolitis in Children From 2 Months to 12 Months at the Children's Hospital 1 in Ho Chi Minh City - Vietnam

• Conditions: Epidemiological, Clinical, Paraclinical Characterictics of Severe Bronchiolitis
• Interventions: Biological: severe bronchiolitis

• Registration Number: NCT04174430
• Lead Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City

Brief Summary

Goal: The aim of this study is to determine the epidemiological, clinical, paraclinical characteristics and treatment of severe bronchiolitis at the Children Hospital N01 in 2001-2002.

Materials and method: in this cross-sectional study, specimens of 51 patients with severe bronchiolitis at the Children Hospital N01 from March, 1 st 2001 to February, 28th 2002 are described and analyzed.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-08-01
• Status Verified: 2019-11
• Study First Submitted: 2019-11-16
• Study First Submitted QC: 2019-11-21
• Last Update Submitted: 2019-11-21
• Study First Posted: 2019-11-22
• Last Update Posted: 2019-11-25
• Primary Completion: 2019-12-01
• Study Completion: 2019-12-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 51

Inclusion Criteria

• children younger from 2-12 months present fever (usually ≤38.3ºC [101ºF]) ,cough, and respiratory distress (eg, increased respiratory rate, retractions, wheezing, crackles)
• preceded by a one- to three-day history of upper respiratory tract symptoms (eg, nasal congestion and/or discharge) ]
• Respiratory distress.

Exclusion Criteria

• refusal to give informed consent
• mucus sample Barlett <=0

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
mild to moderate bronchiolitis	severe bronchiolitis	Bronchiolistis patients without Prematurity (gestational age ≤36 weeks), Low birth weight, Age less than 12 weeks, Chronic pulmonary disease, particularly bronchopulmonary dysplasia (also known as chronic lung disease), Anatomic defects of the airways, Hemodynamically significant congenital heart disease, Immunodeficiency and Neurologic disease

Primary Outcome Measures

Name	Time	Method
Number of participants with Severe bronchiolitis at the Children Hospital N01	2 years	Bronchiolitis in infants with: * Preterm birth : gestational age \< 37 weeks; * Respiratory failure: * Irritable condition; * Breath rate \> 50 per minute; * Hypoxiemia: SpO2 \< 94%; * Poor feeding; * Hemodynamically significant congenital heart disease (congennital heart failure, moderate to severe pulmonary hypertension or cyanotic heart disease)

Trial Locations

Locations (1)

Respiratory; 🇻🇳 Ho Chi Minh City, District 10, Vietnam