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Clinical Trials/NCT02938039
NCT02938039
Completed
Not Applicable

I-Gel vs Ambu Laryngeal Mask Airways in Infants and Children Undergoing Surgical Procedures: A Randomized Clinical Trial

King Saud University0 sites112 target enrollmentMay 2015
ConditionsLaryngeal Masks

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Laryngeal Masks
Sponsor
King Saud University
Enrollment
112
Primary Endpoint
Airway Leak Pressure
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

This study will guide the anesthetists regarding the appropriate selection of the LMA in neonatal age group based on scientific basis.

This study will add up to existing literature about the safety of LMA usage in neonates and infants. Furthermore it may shed some light on which LMA type will be more feasible and effective for neonatal/ infants usage.

Detailed Description

Laryngeal mask airways (LMAs) are in practice of anesthesia since early 1980s. Pediatric and neonatal patients (including ex-premature) have also been benefited by the use of LMA. There are many advantages of LMA over endotracheal tube (ETT) in pediatric patients like ease of insertion, securing airway rapidly, avoidance of muscle relaxants, reduced incidence of sore throat, post operative hoarseness and coughing at the time of extubation, greater hemodynamic and intraocular pressure (IOP) stability. LMA has been recognized internationally in control of airway in difficult and failed intubation. There are different types of pediatric LMAs available e.g. I-gel, ProSeal, LMA supreme, LMA classic, LMA unique, LarySeal and Ambu. These devices differ morphologically from each other (silicone, polyvinyl chloride or soft gel). There have been several randomized controlled studies comparing different LMAs in adults, however, the literature is sparse in which such comparison has been made in patients with weight 10 kg or below.

Registry
clinicaltrials.gov
Start Date
May 2015
End Date
October 2016
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Dr Abdulrahman Alzahem

Associate Professor and Consultant

King Saud University

Eligibility Criteria

Inclusion Criteria

  • Elective surgical procedures
  • No muscle relaxant agents
  • No other comorbidities

Exclusion Criteria

  • Emergency surgical procedures
  • Full stomach
  • Subjects with upper respiratory tract infection
  • Failed caudal block

Outcomes

Primary Outcomes

Airway Leak Pressure

Time Frame: 17 months

It will be measured in mmHg unit and the expiratory valve will be closed with a fresh gas flow of 3 l.min-1 until an audible leak is heard, airway pressure will not be allowed to exceed 25 cmH2O), and then released completely

Secondary Outcomes

  • Success at first attempt(18 months)
  • Oxygen Desaturation less than 90%(18 months)
  • Gastric Insufflation(18 months)
  • Manipulation of the Device(18 months)
  • Effective airway time(18 months)
  • Ease of insertion(18 months)

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