effect of numbing the nerve supplying the lower jaw for cancer surgery on the jaw
- Conditions
- Health Condition 1: null- All adult patients below 75 yrs, ASA I and II PS requiring maxillofacial cancer surgery requiring unilateral mandibular resection and unilateral neck dissection
- Registration Number
- CTRI/2018/04/012996
- Lead Sponsor
- Tata Memorial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 50
INCLUSION CRITERIA - All patients between the age of 18 and 75 yrs classified as ASA I and II physical status requiring maxillofacial cancer surgery requiring unilateral mandibular resection and unilateral neck dissection
EXCLUSION CRITERIA :
-surgery involving upper alveolar / maxillary resection
-patients with BMI below 18kg/m2 and above 30kg/m2
-allergy to local anaesthetic agent
-Inability to give inferior alveolar nerve block due to any cause e.g.
orestricted mouth opening
oobscured landmark or infection at site
-pregnant women
-patients unable to give valid consent e.g. patients with learning difficulties
-patients on medications for hypertension
-patients with preoperative pain requiring regular pain medications
-uncontrolled haemodynamic status e.g. baseline arterial blood pressure above 160 /90 and baseline HR above 100 /min
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.PRIMARY ENDPOINT â?? IV fentanyl requirement during primary tumour removal in the 2 groups <br/ ><br>Timepoint: Time of completion of primary tumour removal
- Secondary Outcome Measures
Name Time Method 1.IV fentanyl requirement during neck dissection and primary tumour removal <br/ ><br>2.Maximum change in heart rate from baseline during primary tumour removal <br/ ><br>3.Maximum change in blood pressure from baseline during primary tumour removal <br/ ><br>4. Need for rescue analgesics or vasoactive agents during primary tumour removal <br/ ><br>Timepoint: 1.Time of completion of primary tumour removal <br/ ><br>2. Time of completion of neck dissection