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Clinical Trials/NCT07366138
NCT07366138
Recruiting
Not Applicable

Ultrasound-Guided External Oblique Intercostal Plane Block Versus Subcostal Transversus Abdominis Plane Block For Perioperative Analgesia in Laparoscopic Sleeve Gastrectomy

Benha University1 site in 1 country70 target enrollmentStarted: November 1, 2025Last updated:

Overview

Phase
Not Applicable
Status
Recruiting
Enrollment
70
Locations
1
Primary Endpoint
Total morphine consumption

Overview

Brief Summary

This study aims to compare the analgesic efficacy, duration of analgesia, and overall opioid consumption between the external oblique intercostal plane (EOIP) block and subcostal transversus abdominis plane (TAP) block in patients undergoing laparoscopic sleeve gastrectomy.

Detailed Description

Postoperative pain management is a critical aspect of enhanced recovery after surgery (ERAS) protocols, particularly in laparoscopic bariatric procedures such as sleeve gastrectomy.

Among the ultrasound-guided abdominal wall blocks, the transversus abdominis plane (TAP) block and its subcostal variant have demonstrated efficacy for upper abdominal surgeries. The subcostal TAP block provides analgesia for the T6-T9 dermatomes, covering incisions in upper abdominal procedures like laparoscopic cholecystectomy and bariatric surgery.

The external oblique intercostal plane (EOIP) block is a relatively new fascial plane block that targets the intercostal nerves lying between the external oblique and intercostal muscles.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
Double (Participant, Outcomes Assessor)

Eligibility Criteria

Ages
18 Years to 65 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Age from 18 to 65 years.
  • Both genders.
  • American Society of Anesthesiologists (ASA) class I or II
  • Body mass index (BMI) between 30-50 kg/m².
  • Scheduled for elective laparoscopic sleeve gastrectomy under general anesthesia.
  • Written informed consent from patients or surrogate decision makers.

Exclusion Criteria

  • Patient refusal.
  • Allergy to local anesthetics.
  • Coagulation disorders or anticoagulant therapy.
  • Local infection or scar at the injection site.
  • Severe hepatic or renal dysfunction.
  • Chronic opioid use or psychiatric illness interfering with pain assessment.
  • Conversion to open surgery or intraoperative complications requiring re-exploration.

Arms & Interventions

EOIP Group (Group A )

Experimental

Patients will receive an ultrasound-guided bilateral external oblique intercostal plane (EOIP) block using 20 mL of 0.25% bupivacaine in each side after induction of anesthesia and prior to surgical incision.

Intervention: External oblique intercostal plane block (Other)

Subcostal TAP Group (Group T)

Experimental

Patients will receive a bilateral subcostal transversus abdominis plane (TAP) block using 20 mL of 0.25% bupivacaine in each side, under ultrasound guidance and identical conditions.

Intervention: Subcostal transversus abdominis plane block (Other)

Outcomes

Primary Outcomes

Total morphine consumption

Time Frame: 24 hours postoperatively

Patient-controlled analgesia (PCA) using intravenous morphine (1 mg bolus, 10-minute lockout) will be available for rescue analgesia when visual analogue score ( VAS ) \> 3.

Secondary Outcomes

  • Time to first rescue analgesia(24 hours postoperatively)
  • Degree of pain(24 hours postoperatively)
  • Heart rate(Till the end of surgery (Up to two hours))
  • Mean arterial blood pressure(Till the end of surgery (Up to two hours))
  • Incidence of postoperative nausea and vomiting(24 hours postoperatively)
  • Block-related complications(24 hours postoperatively)
  • Degree of patient satisfaction(24 hours postoperatively)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Ahmed Alaa El din Ali

Resident of Anesthesiology, Egypt.

Benha University

Study Sites (1)

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