The Effectiveness of Neurodynamic Nerve Mobilization in Addition to Physical Therapy on the Median Nerve and Abductor Pollicis Brevis Muscle in Patients With Mild and Moderate Carpal Tunnel Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 86
- 试验地点
- 1
- 主要终点
- Ultrasound assessment
研究概览
简要总结
This randomized, clinical, single-blinded, controlled study will initially planned to include 86 patients diagnosed with carpal tunnel syndrome who applied to Kütahya Health Sciences University, Evliya Çelebi Training and Research Hospital, Physical Medicine and Rehabilitation outpatient clinic and Kutahya City Hospital.Patients aged 20-55 years who were diagnosed with mild and moderate carpal tunnel syndrome by electromyography (EMG) in the last 6 months were included in the study. The patients were randomized into two groups using the computer-assisted randomization method. Median nerve mobilization and ultrasound therapy will be given to the study group, and only ultrasound therapy will be given to the control group. All the patients were evaluated with the Visual Analog Scale (VAS), Hand and Pinching Grip Test, Boston Carpal Tunnel Questionnaire (BCTQ) and Median Nerve and Abductor Pollicis Brevis Muscle ultrasonography before the intervention and at the third week of intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosed with mild-to-moderate CTS on the dominant hand, based on the electrodiagnostic examination.
- •Aged 20-55 years.
- •Consent to receive the described treatment.
- •Lasting symptoms at least 3 months
排除标准
- •A systemic inflammatory disease.
- •Any disease that can cause polyneuropathy, for example, diabetes mellitus.
- •A cognitive disorder.
- •Receiving psychotherapy.
- •A pacemaker.
- •Any disease that can affect the central nervous system.
- •Carpal tunnel syndrome surgery history
研究组 & 干预措施
Median nerve mobilization in addition to ultrasound therapy
In addition nerve mobilization, ultrasound therapy will be applied to all patient in experimental group via methods explained below.
干预措施: Median Nerve Mobilization (Other)
Median nerve mobilization in addition to ultrasound therapy
In addition nerve mobilization, ultrasound therapy will be applied to all patient in experimental group via methods explained below.
干预措施: Ultrasound therapy (Other)
Ultrasound therapy
In control group, patients will received only ultrasound therapy.
干预措施: Ultrasound therapy (Other)
结局指标
主要结局
Ultrasound assessment
时间窗: Change from Baseline at 3th weeks
The Median nerve's diameter will be evaluated bilaterally by another researcher blinded to interventions and experienced in musculoskeletal ultrasonography, using ultrasound with a 6-18 Mhz linear probe (Mindray-UMT 200, USA). During the examination, patients will be seated on a stretcher, while the examiner sat on a higher stool. The Median nerve will be evaluated by measuring the circumference of the nerve at the location where the nerve entered the carpal tunnel. The ultrasound probe will be positioned above the epicondylus lateralis. The nerve cross-sectional area (CSA) will be recorded in the carpal tunnel while it was perpendicular to the wrist at 90 degrees on the Median nerve trace. The nerve diameter will be measured from the circumference of the epineurium.
次要结局
- Hand and pinching grip measurement(Change from Baseline at 3th weeks)
- Symptom severity and functional status(Change from Baseline at 3th weeks)
研究者
Merve Akdeniz Leblebicier
MD
Kutahya Health Sciences University