The Effect of Adding a Parasternal Intercostal Plane Block to a Serratus Anterior Plane Block on Postoperative Opioid Consumption in Breast Reduction Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Total postoperative opioid consumption in the first 24 hours
研究概览
简要总结
This study aims to evaluate the effect of adding a Superficial Parasternal Intercostal Plane Block (PIPB) to the Serratus Anterior Plane Block (SAPB) on postoperative pain control in patients undergoing breast reduction surgery under general anesthesia. Effective postoperative analgesia is essential to reduce opioid consumption and improve recovery.
All patients will receive standard general anesthesia. Patients will be allocated into three groups: a control group receiving no regional block, a group receiving SAPB alone, and a group receiving SAPB combined with PIPB. The primary outcome of the study is total opioid consumption within the first 24 hours after surgery. Secondary outcomes include postoperative pain scores, Quality of Recovery-15 (QoR-15) scores, and intraoperative remifentanil consumption.
The study aims to determine whether SAPB reduces postoperative opioid requirements compared to no block, and whether adding PIPB provides additional analgesic benefit by blocking the anterior cutaneous branches of the intercostal nerves. The findings may contribute to improving multimodal analgesia strategies in breast surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Female patients aged 18-65 years
- •Scheduled for elective breast reduction surgery under general anesthesia
- •American Society of Anesthesiologists (ASA) physical status I-III
- •Ability to understand the study and provide written informed consent
排除标准
- •Patient refusal
- •Known allergy to local anesthetics
- •Coagulopathy or ongoing anticoagulant therapy
- •Infection at the block site
- •Chronic opioid use or opioid dependence
- •Severe hepatic or renal insufficiency
- •Pregnancy or breastfeeding
研究组 & 干预措施
control
patients receive standard general anesthesia
Serratus Anterior Plane Block
patients receive an ultrasound guided anterior serratus plane block in addition to general anesthesia before surgery
干预措施: Serratus Anterior Plane Block (SAPB) (Procedure)
Serratus Anterior Plane Block + Parasternal Intercostal Plane Block
patients receive an ultrasound guided anterior serratus plane block combined with a parasternal plane block in addition to general anesthesia before surgery
干预措施: Serratus Anterior Plane Block (SAPB) and parasternal intercostal plane block (Procedure)
结局指标
主要结局
Total postoperative opioid consumption in the first 24 hours
时间窗: First 24 hours after surgery
Total opioid consumption during the first 24 postoperative hours will be recorded and compared between the study groups.
次要结局
- Quality of recovery by using QoR-15 questionnaire(postoperative 24th hour)
- Pain Scores(postoperative 0, 1, 2, 6, 12, 24 th hour)
研究者
emine bayraktar
MD
Zonguldak Bulent Ecevit University