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临床试验/NCT01943981
NCT01943981Unknown不适用

Exercise Performance in Patients With Atrial Fibrillation: Usefulness of Cardiopulmonary Exercise Test

Incheon St.Mary's Hospital1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2013年9月最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
50
试验地点
1
主要终点
Exercise response patterns of heart rate and oxygen uptake

研究概览

简要总结

Heart failure and stroke are the two major complication of atrial fibrillation. Current treatment for atrial fibrillation is so focused to stroke prevention, but the risk assessment for heart failure is less highlighted. The most of patients with atrial fibrillation have cardiac functional limitation of variable degree. We hypothesize that the exercise test would reveal the subclinical cardiac dysfunction, and might be helpful to classify the patients with atrial fibrillation according to their exercise capacity real cardiac function.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
30 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Nonvalvular chronic atrial fibrillation
  • Left ventricular ejection fraction >40%

排除标准

  • Acute decompensated heart failure within 30 days
  • unstable hemodynamic status
  • Significant coronary artery disease
  • Any condition interfering sufficient exercise
  • Valvular stenosis or regurgitation of moderate or severe degree
  • Obstructive or restrictive lung disease of moderate or severe degree
  • Active malignancy

结局指标

主要结局

Exercise response patterns of heart rate and oxygen uptake

时间窗: At baseline

次要结局

  • Composite cardiovascular events (all death, admission of heart failure, stroke/thromboembolism)(Up to 2 years)

研究者

发起方
Incheon St.Mary's Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Mi-Jeong Kim

Assistant professor

Incheon St.Mary's Hospital

研究点 (1)

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