Exercise Performance in Patients With Atrial Fibrillation

• Conditions: Atrial Fibrillation

• Registration Number: NCT01943981
• Lead Sponsor: Incheon St.Mary's Hospital

Brief Summary

Heart failure and stroke are the two major complication of atrial fibrillation. Current treatment for atrial fibrillation is so focused to stroke prevention, but the risk assessment for heart failure is less highlighted. The most of patients with atrial fibrillation have cardiac functional limitation of variable degree. We hypothesize that the exercise test would reveal the subclinical cardiac dysfunction, and might be helpful to classify the patients with atrial fibrillation according to their exercise capacity real cardiac function.

Detailed Description

Not available

Study Timeline

• Status Verified: 2013-09
• Study Start: 2013-09
• Study First Submitted: 2013-09-12
• Study First Submitted QC: 2013-09-12
• Last Update Submitted: 2013-09-12
• Study First Posted: 2013-09-17
• Last Update Posted: 2013-09-17
• Primary Completion: 2015-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Nonvalvular chronic atrial fibrillation
• Left ventricular ejection fraction >40%

Exclusion Criteria

• Acute decompensated heart failure within 30 days
• unstable hemodynamic status
• Significant coronary artery disease
• Any condition interfering sufficient exercise
• Valvular stenosis or regurgitation of moderate or severe degree
• Obstructive or restrictive lung disease of moderate or severe degree
• Active malignancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Exercise response patterns of heart rate and oxygen uptake	At baseline

Secondary Outcome Measures

Name	Time	Method
Composite cardiovascular events (all death, admission of heart failure, stroke/thromboembolism)	Up to 2 years

Trial Locations

Locations (1)

Incheon St.Mary's Hospital; 🇰🇷 Incheon, Korea, Republic of