Assessment of Growth in Children With Congenital Heart Disease in Assuit University Children Hospital
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 72
- 试验地点
- 2
- 主要终点
- Weight-for-age z-score in children with congenital heart disease
研究概览
简要总结
Children with congenital heart disease (CHD) often experience growth problems. This study aims to assess and compare the growth (weight, height, head circumference) of infants and children with CHD against the expected growth standards for healthy children. This is a retrospective study that will review the medical records of children aged 1 month to 2 years who were diagnosed with CHD at Assiut University Children Hospital. The study will help understand how different types of CHD affect a child's growth, which is important for improving their nutritional care and overall management.
详细描述
Background:
Congenital heart disease (CHD) is the most common type of congenital anomaly and a leading cause of morbidity in children. Despite advances in medical and surgical care, growth retardation remains a frequent comorbidity in this population. The pathophysiology of growth failure differs between cyanotic and acyanotic CHD, involving factors such as chronic hypoxemia, increased metabolic demands, feeding difficulties, and congestive heart failure. A detailed assessment of growth patterns in children with CHD is crucial for optimizing nutritional interventions, determining the timing of surgical repair, and improving long-term outcomes.
Objective:
The primary objective of this study is to define the impact of congenital heart disease on the somatic growth of infants and children. This will be achieved by comparing anthropometric parameters (weight, height/length, and head circumference) of patients with CHD to established growth standards for healthy children.
Study Design:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 1 Month 至 2 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children aged 1 month to 2 years.
- •Diagnosis of congenital heart disease (CHD) confirmed by echocardiography.
- •Availability of anthropometric data in the medical record.
排除标准
- •Presence of a known genetic syndrome or major extracardiac anomalies.
- •Pre-existing endocrine or metabolic disorder affecting growth.
- •Preterm birth (gestational age <37 weeks).
- •Previous surgical/interventional procedure for CHD.
研究组 & 干预措施
CHD Group
Infants and children aged 1 month to 2 years who were diagnosed with congenital heart disease (CHD) by echocardiography at Assiut University Children Hospital. This is a retrospective cohort; data on anthropometric measurements (weight, height/length, head circumference), type of CHD (cyanotic vs. acyanotic), and clinical history are collected from existing medical records. The growth parameters of this cohort will be compared against standard WHO or Egyptian growth reference charts to assess the impact of CHD on somatic growth.
结局指标
主要结局
Weight-for-age z-score in children with congenital heart disease
时间窗: At study enrollment (data extracted from medical records for age points 6, 12, and 18 months where available).
Comparison of the mean weight-for-age z-score in children with congenital heart disease (CHD) against the standard population mean (z-score = 0) using WHO or Egyptian growth reference charts.
次要结局
未报告次要终点
研究者
Lamia Mohammed Hussain Mohammed
Resident Doctor at Al-Mabrah Hospital
Assiut University