Intraoperative Perineural Injection of Lidocaine for Postlaminectomy Pain
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- In the laminectomy operation, right after the exposure of the dorsal root , an injection of lidocaine attenuates postoperative pain.
研究概览
简要总结
To relieve post laminectomy pain, we have tried intraoperative perineural injection of lidocaine right after the exposure in expecting that this would be preemptive analgesia by blocking the nerve transmission so that postoperative pain starts later and lighter.
详细描述
A randomized double-blind 40 patients aged 18-50 of ASA I and II undergoing laminectomy were included in the study. All the patients were followed for their heart rate, arterial pressure , respiratory rate, oxygen saturation, end tidal CO2 and postoperative VAS scores.
All the patients were premedicated with midazolam 0.1 mg/kg intramuscularly 40 minutes prior to surgery. The induction was made 2 mg/kg propofol, 1 ug/kg remifentanyl, 0.5mg/kg rocuronium. After the orotracheal intubation anesthesia was maintained with isoflurane (%0.5-2.0) and 0.1 mg/kg rocuronium.Just before the exposure of dorsal root, 0.5 cc %2 lidocaine was injected on the dorsal root.The patients postoperative analgesic period, VAS scores and additional analgesic need was recorded. For the postoperative analgesia tramadol 1 mg/kg tramadol was used.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •laminectomy
- •18-50 age
排除标准
- •under 18 or older than 50
- •any disease other than back pain\
研究组 & 干预措施
A01L
干预措施: Lidocaine, perineural injection, intraoperatively (Drug)
A01L
干预措施: Lidocaine (Drug)
结局指标
主要结局
In the laminectomy operation, right after the exposure of the dorsal root , an injection of lidocaine attenuates postoperative pain.
时间窗: postoperative 24 hours
次要结局
未报告次要终点