A multi-centre, randomized, double-blind trial studying the effect of misoprostol on the outcome of intra-uterine insemination.
Completed
- Conditions
- Intra-uterine insemination, misoprostol, pregnancy, prostaglandin, vaginal suppository.
- Registration Number
- NL-OMON29376
- Lead Sponsor
- Prof. Dr. M. Dhont, Vrouwenziekten, De Pintelaan 185, 9000 Gent, Belgium, Marc.Dhont@Ugent.be, 0032/9240.37.96.
- Brief Summary
Gynecol Obstet Invest. 2008 May 20;66(3):145-151. [Epub ahead of print]
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 217
Inclusion Criteria
1. All women presenting for intra-uterine insemination;
2. Between the age of 20 and 36 years;
Exclusion Criteria
1. History of previously failed intra-uterine insemination;
2. Severe comorbidity (endometriosis, fibroma);
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary outcome is clinical pregnancy defined as the presence of a fetal sac with positive cardial activity.
- Secondary Outcome Measures
Name Time Method Secondary endpoints are adverse reactions: uterine cramps and vaginal bleeding.