NCT02485444已完成4 期
Oxytocin Infusion vs. Spontaneous Follow-up for Third-stage Management After Second-trimester Abortion: A Randomized Clinical Trial
适应症
干预措施
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 160
- 试验地点
- 1
- 主要终点
- Complete abortion rate
研究概览
简要总结
This study compares oxytocin infusion to spontaneous follow-up for third-stage of labor at induced mid-trimester abortions. Patients will be randomized to oxytocin infusion or observation with no pharmacologic intervention. Primary outcome of the study is complete abortion rate within two hours of fetal delivery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 17 Years 至 45 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Women who had mid-trimester termination of pregnancy between 13-24 gestational weeks
排除标准
- •If fetus and placenta expelled together
- •Obstetrical haemorrhage needs intervention
- •Known prostaglandin allergy
研究组 & 干预措施
Oxytocin
Active Comparator
干预措施: Oxytocin (Drug)
结局指标
主要结局
Complete abortion rate
时间窗: within 5 minute after placenta delivered
expulsion of placenta completely without an instrumental assistance within two hours after delivery of fetus
次要结局
- Blood loss estimated by gravimetric method(within 10 minutes after delivery of placenta)
- Transfusion rate(Within 7 days of hospitalization)
- Change in hemoglobin measured by difference in hemoglobin before and 24-hour after abortion(24 hours after delivery of placenta)
- Placenta delivery time measured by time elapsed until the delivery of the placenta from the delivery of foetus(5 minute after delivery of placenta)
研究者
Ragıp Atakan Al
professor
Ataturk University
研究点 (1)
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