跳至主要内容
临床试验/NCT06422598
NCT06422598招募中不适用

Prevalence and Management Practice of Diabetic Kidney Disease at BADAS Affiliated Healthcare Centres in Bangladesh - An Exploratory Cross-Sectional Study

Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders8 个研究点 分布在 1 个国家目标入组 320 人开始时间: 2024年5月11日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
320
试验地点
8
主要终点
Prevalence of diabetic kidney disease

研究概览

简要总结

Background: Diabetes is a growing public health concern in Bangladesh, with millions affected. Diabetic Kidney Disease (DKD) is a severe complication of diabetes, affecting approximately 21.3% of the diabetic population. To address this issue, a comprehensive assessment of DKD within the Bangladesh Diabetic Association's (BADAS) affiliated healthcare centres is necessary.

Objective: The study's general objective is to determine the prevalence of DKD and evaluate its management at BADAS-affiliated healthcare centers. Specific objectives include assessing risk factors, screening practices, disease staging, management approaches, patient education, and providing evidence-based recommendations.

Methodology:

  • Study Design: Cross-sectional
  • Study Population: All diabetic patients at BADAS-affiliated centers
  • Exclusion Criteria: Patients unwilling to participate or with kidney disease from other causes and with acute illness
  • Sample Size: "Forty patients will be selected from each center, resulting in a total sample size of 320 patients across eight centers, with one center randomly selected from each of the eight divisions in Bangladesh."
  • Data Collection: Demographics, comorbidities, kidney function, blood pressure, HbA1c levels, medication records, treatment guideline adherence
  • Data Analysis: prevalence of diabetic kidney disease, factors affecting management, and potential barriers
  • Ethical Considerations: Ensure patient data privacy, obtain approvals, and informed consent Implications: The study aims to provide insights into the current state of magnitude (prevalence) of DKD, its management, highlighting areas for improvement in patient care, guideline adherence, and ultimately enhancing the well-being of diabetic patients in Bangladesh.

详细描述

Background: Diabetes mellitus represents a significant public health challenge globally, and Bangladesh is no exception to this growing epidemic. According to the International Diabetes Federation (IDF), about 13.1 million people in Bangladesh have diabetes, and this number is expected to increase to 22.3 million by 2045(Sun et al., 2022). One of the most serious complications of diabetes is Diabetic Kidney Disease (DKD), which can lead to chronic kidney disease and end-stage renal disease (ESRD). DKD not only imposes a heavy burden on the healthcare system but also affects the economic and social well-being of the patients and their families. The prevalence of kidney disease among the diabetic population of Bangladesh is estimated to be around 21.3%. This number is based on a single center study conducted at the Bangladesh Institute of Health Sciences (BIHS) hospital in Dhaka, Bangladesh(Islam et al., 2021). This high prevalence highlights the need for a comprehensive evaluation of DKD within the centers affiliated with the Bangladesh diabetic association (BADAS), which is the largest non-governmental organization providing diabetes care and research in the country.

The Bangladesh Diabetic Association (BADAS), with its extensive network of diabetes care centers and healthcare professionals, has long been at the forefront of addressing diabetes-related health concerns in the country. As a nation-wide institution dedicated to diabetes care, BADAS plays a pivotal role in delivering healthcare services and shaping the well-being of diabetic patients in Bangladesh.

A comprehensive understanding of DKD prevalence and management status within BADAS centers is essential to enhance the quality of care for diabetic patients. Identifying areas for improvement is the first step towards effecting positive change.

Our ultimate plan is to implement a nationwide DKD prevention program through affiliated diabetic centers. To achieve this, a comprehensive assessment of the current situation is an imperative foundation for program design, planning, and execution.

The study will provide a rich dataset upon which evidence-based recommendations for preventing and managing DKD within BADAS-affiliated centers can be developed. These recommendations are essential for improving patient outcomes and ensuring the success of the future prevention program.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All registered diabetic patients receiving care at affiliated healthcare centres of Bangladesh Diabetic Associations.

排除标准

  • Unwilling to participate in the study.
  • Presence of AKI or acute illness
  • Presence of Known kidney disease due to other cause.
  • Pregnancy

结局指标

主要结局

Prevalence of diabetic kidney disease

时间窗: Day 1

Calculate the prevalence of DKD among diabetic patients visiting BADAS-affiliated healthcare centers using clinical and laboratory assessments.

次要结局

  • Risk Factors for DKD(Day 1)
  • Management Approaches(Day 1)
  • Screening Practices(Day 1)

研究者

发起方
Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders
申办方类型
Other
责任方
Principal Investigator
主要研究者

Wasim Md Mohosin Ul Haque

Professor

Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders

研究点 (8)

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