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Impact of Stress Management Training After Cardiac Transplantation

Phase 3
Conditions
Heart Transplant
Interventions
Behavioral: Stress management
Registration Number
NCT02163629
Lead Sponsor
Hospices Civils de Lyon
Brief Summary

In spite of major medical advances in heart transplant patients, psychiatric comorbidity remains very high in pre-and post-transplant phases. Anxiety and depression are especially frequent. They impact significantly morbidity and mortality. Especially because they are associated with poor therapeutic adherence and risks of infection and rejection. The inability to make beneficial therapeutic choice can be explained by the negative perception of events, associated with anxio-depressive disorders. This results in an important deterioration in quality of life of patients.

The investigators assume that better management of emotions might reduce the stress of waiting situation and its psychopathological and somatic consequences pre-and post-transplant.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
60
Inclusion Criteria
  • Men and women on the cardiac transplantation waiting list
  • Patients aged 18 years and older
  • Signed written informed consent
  • Patients under the social security
  • Patients with a somatic condition allowing travels
  • Patients mastering the French language
  • Class II or III NYHA patients
Exclusion Criteria
  • Patients minor or under protection measures
  • Patient who have not signed written informed consent
  • Patients not mastering the French language
  • Patients with psychiatric illness characterized by the axis 1 of DSM IV R
  • Patients receiving a psychotherapy or with a psychiatric care
  • class IV NYHA patients

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
psychotherapeutic interventionStress managementThe psychotherapeutic intervention "stress management" is based on therapeutic, behavioral and cognitive strategies. They are active and put the patient "actor" of his "adaptation" of the heart transplantation entire process. The approached components are emotional, cognitive and behavioral (techniques of communication and problem solving).
Primary Outcome Measures
NameTimeMethod
Evaluation of the impact of a psychotherapeutic intervention on the quality of life of cardiac transplant patients.The quality of life is evaluated before the cardiac transplantation and during the 12 months after the cardiac transplantation.

The quality of life is assessed with the MLHFQ - Minnesota Living with Heart Failure Questionnaire.

Secondary Outcome Measures
NameTimeMethod
Anxiety manifestations pre-and post-transplantBefore the cardiac transplantation and during 12 months after the cardiac transplantation

Anxiety manifestations pre-and post-transplant measured with the State-Trait Anxiety Inventory

Somatic complications after the heart transplantationDuring 12 months after the cardiac transplantation

by measuring the mortality rate and number of graft rejection

Pre and post-transplant major clinical eventsBefore the cardiac transplantation and during 12 months after the cardiac transplantation
Hospitalization modalities around the graftBefore the cardiac transplantation and during 12 months after the cardiac transplantation

by measuring the duration of stay in hospital, number of surgery necessary

Depressive symptoms pre-and post-transplantBefore the cardiac transplantation and during 12 months after the cardiac transplantation

depressive symptoms pre-and post-transplant measured using the Beck Depression Inventory (BDI-II)

The therapeutic adherence pre-and post-transplantBefore the cardiac transplantation and during 12 months after the cardiac transplantation

using an adherence questionnaire

Trial Locations

Locations (2)

Service de Psychiatrie d'Adultes Liaison/Consultation,

🇫🇷

Bron, France

Pôle de Psychiatrie et de Neurologie

🇫🇷

Grenoble, France

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