跳至主要内容
临床试验/CTRI/2025/10/096306
CTRI/2025/10/096306招募中不适用

Effect of prehabilitation on post-operative hypocalcemia in patients undergoing total thyroidectomy.

Datta Meghe Institute of Higher Education and Rsearch1 个研究点 分布在 1 个国家目标入组 23 人开始时间: 2025年11月2日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
23
试验地点
1
主要终点
This study will help to evaluate the role of pre operative correction ( pre habilitation) of hypocalcemia and hypovitaminosis D in preventing post op hypocalcemia in pts undergoing total thyroidectomy. It will also help us to evaluate the role of early operative levels of serum parathormone levels to predict post operative hypocalcemia/hypoparathyroidism and risk of protracted hypocalcemia.

研究概览

简要总结

It is a prospective observational study which aims to assess the demographic profile and indications for total thyroidectomy. To estimate the incidence of preoperative hypocalcaemia and hypovitaminosis D3 in patients posted for total  thyroidectomy and to  correct them preoperatively. To evaluate the intra operative findings in terms of whether parathyroid glands are identified at surgery, superior or inferior or both glands are identified, site of ligation of inferior thryoid artery , whether auto transplatation of parathyroid glands is done during surgery.To estimate te incidence of post operative hypothyroidism 24 hours after surgery by Serum iPTH levels. To estimate the incidence of clinical and biochemical hypocalcemia on Day 1 and Day 3 post surgery.

Hypocalcemia is life threatening situation , many patients preoperatively have hypocalcemia and hypo -vitaminosis D , so we try to evaluate pre operative calcium levels with early post operative parathormone level and serum calcium to reduce the risk of post operative hypocalcemia which might lead to permanent hypothyroidism.

This study will help to evaluate the role of pre-operative correction ( prehabiliatation) of hypcalcemia and hypovitaminosis d in preventing post op hypocalcemia in patients undergoing total thyroidectomy.It will also help us evaluate the role of early operative levels of serum parathormone levels to predict post operative hypocalcemia / hypoparathyroidism and risk of protracted hypocalcemia.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • Ages between 18 to 65 years who will be planned for total thyroidectomy.
  • All genders Patients with ASA grade1 and 2 All individuals who are consenting for study.

排除标准

  • Patients who will be lost for follow up .
  • Patients with hypoparathyroidism, renal failure, drugs, ( bicarbonate, rifampicin), hypomagnesemia, acute pancreatitis.
  • Patients who are not consenting.

结局指标

主要结局

This study will help to evaluate the role of pre operative correction ( pre habilitation) of hypocalcemia and hypovitaminosis D in preventing post op hypocalcemia in pts undergoing total thyroidectomy. It will also help us to evaluate the role of early operative levels of serum parathormone levels to predict post operative hypocalcemia/hypoparathyroidism and risk of protracted hypocalcemia.

时间窗: 2 years

次要结局

  • To estimate hypocalcemia in pts undergoing total thyroidectomy(2 years)

研究者

发起方
Datta Meghe Institute of Higher Education and Rsearch
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

E Madhuri

Jawaharal Nehru Medical College

研究点 (1)

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