Iron Overload in people with Sickle Cell Disease: evaluation of the intestinal absorption of this nutrient

niversidade do Estado do Rio de Janeiro0 个研究点开始时间: 2023年7月6日最近更新: 2023年7月26日

适应症

试验速览

暂无简介。

•Children from 2 to 10 years old; adolescents aged 11 to 18 years; adults: from 19 to 59 years old, divided into three groups. In group 1, patients with sickle cell anemia with the SS genotype confirmed by HPLC and who are being followed up at the Hemorio hematology outpatient clinic, with a serum ferritin concentration equal to or greater than 1000 ng/mL; in group 2, patients with sickle cell anemia (SS genotype) confirmed by High Performance Liquid Chromatography (HPLC) and who are followed up at the Hemorio hematology outpatient clinic, with serum ferritin concentration below 1000 ng/mL; in group 3, healthy individuals who do not have sickle cell anemia proven by HPLC

•Participants with sickle cell anemia who have been hospitalized and/or received transfusions in the last 15 days prior to the assessment; individuals in the group without sickle cell anemia who have sickle cell trait or other haemoglobinopathies, hematological diseases and/or who use medication for diabetes mellitus and hypo/hyperthyroidism and/or who have serum ferritin less than 10 ng/mL for women and less than 20 ng/mL for men. Pregnant women were also excluded from both groups.

发起方

niversidade do Estado do Rio de Janeiro