ISRCTN41421863已完成未知
Is intravenous iron and darbepoetin more effective than oral iron in reducing blood transfusion requirements for patients undergoing cardiac surgery? A pragmatic randomised trial
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 320
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Preoperative Hb 10-13 g/dl
- •2. Serum ferritin <100µg/l or 100-800 µg/L with transferrin saturation <30%
- •3. First time cardiac surgery involving one or more of the following: coronary artery bypass grafting, repair or replacement of cardiac valve/s or ascending aorta
- •4. Surgery is elective - not an emergency or patient is not an inpatient immediately prior to surgery
排除标准
- •1. Hb <10 g/dl or >13 g/dl
- •2. Patient intends to refuse allogeneic blood transfusion
- •3. Patient is receiving renal replacement therapy (peritoneal or hemodialysis) before surgery
- •4. Patient has a history of allergic or toxic reaction to any of the study drugs
- •5. Patient has significant acute or chronic hepatic disease
- •6. Patient is undergoing chemotherapy
- •7. Redo cardiac surgery (i.e. second time or more)
- •8. Proposed surgery will require hypothermic circulatory arrest
- •9. Pregnant
- •10. Age <18
- •11. Lacks mental capacity to give consent
- •12. Already participating in another clinical trial that could interfere with this study
研究者
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