Phase II Study of Response of Medical Journal Editorial Boards to Notification of Serious Discrepancies in Published Clinical Trials in Human Patients.
试验速览
- 阶段
- 不适用
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- Time to correction, retraction, or other notification to the readership of discrepancy
研究概览
简要总结
Clinical research, like all science, is self-correcting, with errors detected by the scientific community and communicated to the publishing journals, which then relay the information (and its resolution) to its readers. If this relaying process fails, science grinds to a halt. In this study we are testing its integrity.
详细描述
This prospective study documents the outcome of notification to journal editorial boards (or equivalent authorities) of factually incorrect or inconsistent claims, in reports they have published.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Report of a clinical trial in humans of treatment of heart disease with bone marrow derived stem cells
- •Report containing discrepancy by reference to same report or another report
排除标准
- •Discrepancy has already been corrected by an erratum
研究组 & 干预措施
Provision of information
Reporting of discrepancy to journal
干预措施: Reporting of discrepancy to journal (Behavioral)
结局指标
主要结局
Time to correction, retraction, or other notification to the readership of discrepancy
时间窗: 12 months
次要结局
- Time to initial response from journal(0-4 weeks)
研究者
Darrel Francis
Professor of Cardiology
Imperial College London