Pediatric Relapsing Polychondritis : Diagnosis and Management in a French Retrospective Study
- Conditions
- Relapsing Polychondritis
- Registration Number
- NCT06019221
- Lead Sponsor
- University Hospital, Strasbourg, France
- Brief Summary
The incidence in pediatrics is very low (about 3.5 per million per year according to a 2015 study) and therefore the data on the pathology very poor, especially on the therapeutic level.
Without appropriate treatment, the disabling sequelae, even involving the vital prognosis, are significant. However, in paediatrics, therapeutic habits have been extrapolated from adult data and lack precision.
Existing treatments are almost composed of immunomodulatory and/or immunosuppressive treatments. Different therapeutic lines have been introduced over the years and a better understanding of the pathology. More recently, biotherapies have been introduced in this pathology, but data on their effectiveness remain limited. Data on the evolution under therapy in children are thus still poor.
Complications related to the pathology that can jeopardize the vital prognosis and the response to treatment for this pathology deserve to be studied in order to be known and if possible avoided.
The aim of the study is to describe French practices and compare the lines of treatment proposed for juvenile atrophic polychondritis.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 20
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Therapeutic effectiveness of the various treatments proposed depending on the degree of initial clinical involvement Files analysed retrospectively from from January 01, 2008 to December 31, 2022 will be examined The aim of this study is to bring together the experiences of the various reference and competence centers in France concerning the clinical presentation, management and follow-up of children with relapsing polychondritis.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Service de Pédiatrie 1 - CHU de Strasbourg - France
🇫🇷Strasbourg, France