SAM: Discharge Based on the Use of a MUAC-based Criterion to

Completed

• Conditions: Severe Acute Malnutrition
• Interventions: Other: Discharge from community-based management

• Registration Number: NCT03303131
• Lead Sponsor: Epicentre

Brief Summary

Retrospective analysis of routine program data of children aged 6 to 59 months admitted to the MSF therapeutic feeding program with MUAC ≤ 118 mm in Yako and Titao districts of Burkina Faso from 2007-2011.

Detailed Description

Comparison of patient characteristics and treatment outcomes was conducted between two groups: 1) children discharged as recovered from September 2007 to March 2009 with at least 15% of their weight at admission (Period A); and 2) children discharged as recovered from April 2009 to December 2011 with MUAC ≥ 124 mm (Period B).

A total of 50,841 children were admitted with MUAC ≤ 118 mm to the MSF therapeutic feeding program and were included in this analysis: 24,792 children in Period A (2007-2009) and 26,049 children in Period B (2009-2011).

Overall, 89% of admissions were directly into outpatient care and the majority (53%) entered with a MUAC 116-118mm; 48% of children were male and 80% of children \< 2 years of age (Table 1).

Compared to children admitted in Period A, children admitted in Period B were statistically more likely to be female, younger, and of better anthropometric status (e.g. higher mean MUAC, WHZ and HAZ).

There was a greater proportion of children admitted directly to inpatient care in Period B than in Period A (10.6% vs 8.0%).

Study Timeline

• Study Start: 2007-09-01
• Primary Completion: 2011-12-31
• Study Completion: 2011-12-31
• Study First Submitted: 2017-10-02
• Study First Submitted QC: 2017-10-02
• Study First Posted: 2017-10-05
• Status Verified: 2018-01
• Last Update Submitted: 2018-02-01
• Last Update Posted: 2018-02-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50841

Inclusion Criteria

• 6 to 59 months old
• presence of bipedal pitting edema or MUAC ≤ 118 mm

Read More

Exclusion Criteria

• < 6 months old or > 59 months old
• absence of bipedal pitting edema or MUAC ≥ 118 mm

Read More

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Period A	Discharge from community-based management	Children discharged as recovered from September 2007 to March 2009 with at least 15% of their weight at admission
Period B	Discharge from community-based management	Children discharged as recovered from April 2009 to December 2011 with Children discharged as recovered from September 2007-March 2009 with MUAC ≥ 124 mm

Primary Outcome Measures

Name	Time	Method
MUAC based criterion	52 months	Use of a discharge criterion of MUAC ≥ 124 mm