跳至主要内容
临床试验/NCT00180700
NCT00180700已完成不适用

The Effects of Two Psychological Intervention Techniques, Self-hypnosis and Johrei Healing Method, on Quality of Life, Psychological Well-being, EEG Measures and Various Immunological Measures Including CD4+ Counts in Early HIV: a Randomly Controlled Pilot Study

Imperial College London2 个研究点 分布在 1 个国家目标入组 22 人开始时间: 2003年6月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
22
试验地点
2
主要终点
CD4 T-cell counts

研究概览

简要总结

This study examines the hypothesis that psychological interventions have beneficial effects on quality of life including psychological well-being and disease progression in early HIV patients recieving no medication.

详细描述

Hypothesis

This investigation is based upon the hypothesis that psychological intervention may counteract the detrimental effects of stress both on psychological well-being and on general health.

Background: HIV infection may be considered to be a life-long biological and psychological stressor leading to detrimental outcomes associated with disease progression. Stress reduction in these patients may have beneficial effects through delaying disease progression via the proposed interactive psycho-neuro-endocrine-immune network.

Inclusion Criteria:

HIV infected individuals CD4 T-cell counts above 200 cells/mcl Receiving no anti-retroviral drugs Individuals who signed the informed consent form

Investigative approach: Self-hypnosis and a Japanese non-touching, laying-on-of hands-like technique, called Johrei, were used to investigate the effects of psychological intervention upon immune parameters (especially in CD4 counts) associated with disease progression along with phenomenological associations between stress perception and stress hormone levels in HIV-infected patients receiving no medication.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
Single (Participant)

盲法说明

Single blinded

入排标准

年龄范围
20 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • HIV infected
  • CD4 T-cell counts above 200 cells/mcl
  • Signed the informed consent form

排除标准

  • receiving anti-retroviral drugs

研究组 & 干预措施

Self-hypnosis

Experimental

A course of four weekly 2-hour training sessions coupled with daily self-hypnosis practice was given to 13 participants with diagnosed HIV

干预措施: Hypnosis (Behavioral)

Johrei healing method

Experimental

A course of four weekly 2-hour training sessions coupled with daily self-hypnosis practice was given to 9 participants with diagnosed HIV

干预措施: Hypnosis (Behavioral)

结局指标

主要结局

CD4 T-cell counts

时间窗: 4 weeks

Lab test

次要结局

  • Endogenous hormone levels (cortisol, DHEA-S and melatonin)(4 weeks)
  • Other immunological parameters (Viral load levels, NK cell counts)(4 weeks)
  • Psychological questionnaires (Perceived Stress Scale (PSS), STAI, Beck depression Inventory (BDI))(4 weeks)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

Loading locations...

相似试验

The Influence of Psychological Interventions Upon... | 临床试验