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Clinical Trials/NCT04559997
NCT04559997CompletedNot Applicable

6-year Follow-up Study of the Effectiveness of Neurorehabilitation Treatment in a Patient With Parkinson's Disease

Somogy Megyei Kaposi Mór Teaching Hospital2 sites in 1 country3 target enrollmentStarted: September 1, 2014Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
3
Locations
2
Primary Endpoint
Timed up and Go test

Study Overview

Brief Summary

Individualization of exercise is recommended but rarely performed in patients with Parkinson's disease (PD). Unusually High Intensity and Individual Sensor Motor with Visuomotor Mobility Trainer The clinical symptoms, mobility and posture of PD patients. After 3 weeks of intensive treatment, treated patients and the control group were subjected to a two-year observation. Objectives: The effect of the unusually highly intense and strictly individualized sensomotor and visuomotor agility program was determined for the clinical symptoms, mobility and stability of non-demented PD patients with a two-year follow-up. Detection and comparison of results of patients undergoing biphasic maintenance with the results of intensively treated patients and the control group. Patients were recalled every 3 months after the first intensive examination and one year after a one-year control. The results of the active group were continuously compared with the results of the passive and control groups, thus determining the effectiveness of our treatment and the deterioration of the other groups in life-quality. The treated groups will be divided into two. One Parkinson's group takes part in a treadmill treatment that takes place 3 times a week for 6 years. The other group does not undergo a special series of exercises after 3 weeks of intensive therapy. Main outcome measures: Movement disorder Society Unified Parkinson Disease Rating Scale, Motor Experiences of Daily Living, a measure sensitive to changes in a broad spectrum of PD symptoms. In group time, repeated measurements of variance analysis were compared to MDS-UPDRS M-EDL, Beck Depression Score, PDQ-39, EQ5D VAS, Schwab & England Scale for Parkinson's Disease. The TUG test and 12 static posturographic measurements are compared and compared to the healthy group as a standard. An at-limit and individualized sensorimotor and visuomotor agility exercise program vs. standard care, will improve non-demeted, stage 2-3 PD patient's clinical symptoms, mobility, and postural stability by functionally meaningful margins. As a long-term solution, a follow-up treatment can slow down the progression of clinical symtoms.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
55 Years to 85 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Parkinson's disease
  • Hoenh Yahr scale of 2-3
  • Instability problem

Exclusion Criteria

  • Severe heart problems
  • Severe demeanor
  • Alcoholism
  • Drug problems

Outcomes

Primary Outcomes

Timed up and Go test

Time Frame: 6 year-long

Measuring the speed of walking

EQ5D-5L

Time Frame: 6 years long

Questionnaire

posturography

Time Frame: 6 year-long

body sway, Objective measurement of holding instability

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Somogy Megyei Kaposi Mór Teaching Hospital
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Tollár József

Dr. József Tollár, 7400 Kaposvár, Tallián Gy. u 20-32

Somogy Megyei Kaposi Mór Teaching Hospital

Study Sites (2)

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