ISRCTN10232550已完成未知
Intramuscular oxytocics: a multi-centre randomised comparison study of intramuscular carbetocin, syntocinon and syntometrine for the third stage of labour following vaginal birth
orth Bristol NHS Trust0 个研究点目标入组 5,717 人开始时间: 2018年3月6日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 5,717
研究概览
简要总结
2019 protocol in: https://www.ncbi.nlm.nih.gov/pubmed/30606246
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- Female
入选标准
- •Current inclusion criteria as of 27/06/2018:
- •1. =18 years of age at time of delivery
- •2. Vaginal birth
- •3. Live, singleton pregnancy
- •4. >24 weeks gestation
- •Previous inclusion criteria:
- •1. =18 years of age at time of baby’s birth
- •2. Planning to have a vaginal birth (spontaneous and instrumental)
- •3. Singleton pregnancy
- •4. Any gestational age
排除标准
- •Current exclusion criteria as of 27/06/2018:
- •1. Significant antepartum haemorrhage (>50ml) or suspected or proven placenta abruption
- •2. Maternal coagulation disorder
- •3. Women who would decline blood products if required
- •4. Known or suspected hypertensive disorders
- •5. Peripheral, hepatic or cardiac disease
- •6. Epilepsy
- •7. Patients with an allergy or hypersensitivity to any of the active ingredients of the study drugs
- •Previous exclusion criteria:
- •1. Significant antepartum haemorrhage (>50ml) or suspected or proven placenta abruption
- •2. Maternal coagulation disorder
- •3. Multiple pregnancy (twins or higher order)
- •4. Intrauterine fetal death
- •5. Patients who would decline blood products if required (i.e., Jehovah's Witnesses - clinicians may have a lower threshold for administering additional prophylactic uterotonic drugs to these patients)
- •6. Known or suspected hypertensive disorders, including pre-eclampsia,
- •pregnancy induced hypertension, essential hypertension (even if blood pressure well controlled), and patients with hypertension in labour
- •7. Patients with peripheral, hepatic or cardiac disease
- •8. Patients with an allergy or hypersensitivity to any of the active ingredients in Carbetocin, Syntometrine or Syntocinon
研究者
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