Observational Longitudinal Study in Children Affected by Idiopathic Growth Hormone Deficiency (GHD): Lung Function Parameters Assessment; Quality of Life Assessment; Stress Parenting Assessment (Pneumo GHD)
Overview
- Phase
- Not Applicable
- Intervention
- Growth Hormone-Releasing Hormone
- Conditions
- Growth Hormone Deficiency
- Sponsor
- Stefania La Grutta, MD
- Enrollment
- 48
- Primary Endpoint
- Assessment of the developmental patterns of lung function before and after GH by spirometry
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
The aim of this study is to assess the developmental patterns of lung function in children affected by growth hormone deficiency after one year of GH therapy.The assessment by specific questionnaires of quality of life and of parental stress index.Parameters will be evaluated at the time of the diagnosis and after 12 months of GH therapy.
Detailed Description
Observational longitudinal study in children affected by idiopathic growth hormone deficiency (GHD): lung function parameters assessment; quality of life assessment; stress parenting assessment (Pneumo GHD). The aim of this study is to assess the developmental patterns of lung function in children affected by growth hormone deficiency after one year of GH therapy.The assessment by specific questionnaires of quality of life and of parental stress index.Parameters will be evaluated at the time of the diagnosis and after 12 months of GH therapy.
Investigators
Stefania La Grutta, MD
Stefania La Grutta, MD. Senior Researcher. Coordinator of Pediatric Allergy and Asthma Research Group. Institute of Biomedicine and Molecular Immunology, IBIM, National Research Council of Palermo, Italy.
Istituto per la Ricerca e l'Innovazione Biomedica
Eligibility Criteria
Inclusion Criteria
- •GH deficiency
Exclusion Criteria
- •Respiratory infections 4 weeks before the recruitment
- •Children with autoimmune diseases
- •Therapy with drugs able to modify the lung function
Arms & Interventions
GHD Children
Treatment with Growth Hormone-Releasing Hormone in children affected by idiopathic growth hormone deficiency (GHD)
Intervention: Growth Hormone-Releasing Hormone
Outcomes
Primary Outcomes
Assessment of the developmental patterns of lung function before and after GH by spirometry
Time Frame: 1 year
Assessment of lung function before and after administration of GH in children with growth hormone deficiency by spirometry