Randomized Phase II trial of palonosetron, aprepitant plus dexamethasone for 1 day with or without dexamethasone on days 2 and 3 in the prevention of nausea and vomiting induced by chemotherapy for breast cancer
Phase 2
- Conditions
- breast cancer
- Registration Number
- JPRN-UMIN000006977
- Lead Sponsor
- Kitasato University School of Medicine Department of Surgery
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Not provided
Exclusion Criteria
1)Patients who has a convulsive disorders that need anticonvulsants therapy. 2)With nausea (CTCAE Grade2). 3)A history of sever allergic reaction with palonosetron or aprepitant or dexamethasone. 4)Pregnancy or the desire to preserve fecundity. 5)Receiving an antiemetic drug. 6)Receiving pimozide. 7)With mental disease or psychotic manifestation. 8)Any patients judged by the investigator to be unfit to participate in the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method