The effect of flavonoids from cherries on memory and cognition in older adults with mild to moderate dementia

Completed

• Conditions: Dementia; Diet and Nutrition - Other diet and nutrition disorders; Neurological - Dementias

• Registration Number: ACTRN12614001298606
• Lead Sponsor: Illawarra Health and Medical Research Institute, University of Wollgongong

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-12-11
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

>70years
MMSE score 10 - 24

Exclusion Criteria

MMSE > 24
Confounding health conditions such as dysphasia.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cognitive function was assessed using a battery of seven cognitive tests, including the Rey Auditory Verbal Learning Test (RAVLT), the self-ordered pointing task (SOPT), the Boston naming test, the trail making test (TMT), digit span backwards task and category and letter verbal fluency.[6 weeks and 12 weeks after baseline]

Secondary Outcome Measures

Name	Time	Method
Anthropometrics including height, weight and muscle mass measured using bioelectric impedence scales. [6 and 12 weeks post baseline.];Biomarkers of inflammation - IL-6 and CRP measured using a serum assay.[6 and 12 weeks after baseline];Depression measured using Geriatric Depression Scale[6 and 12 weeks after baseline];Blood pressure measured using an OMRON blood pressure monitor, at rest and in triplicate. [6 and 12 weeks after baseline.];Hand-grip strength measured using a JAMAR hand grip dynomometer.[6 and 12 weeks after baseline.];Mid-arm and mid-calf measurements were recorded using a standard measuring tape.[6 and 12 weeks post baseline.]