Randomized phase II syudy of weekly docetaxel versus S-1 and concurrent radiothrapy for stage III and IV laryngeal, oropharyngeal, and hypopharyngeal cancer in elderly patients or patients with complications
- Conditions
- laryngeal, oropharyngeal, and hypopharyngeal cancer
- Registration Number
- JPRN-UMIN000001144
- Lead Sponsor
- study group of chemoradiotherapy of the head and neck cancer
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 60
Not provided
1)with sever complications (for example ; malignant hypertension, congested heart failure, coronary insufficiency, myocardial infarction, angina pectoris, or abnormal cardiac rhythm which need to treat within 6 months, cerebrovascular accident within 6 months, cirrhosis, hemorrhagic gastrointestinal ulceration, diabetes that is loss of control, bleeding tendency) 2)with deverop fever and suspected infection 3)with motor palsy, peripheral neuropathy or edema (exclude the disorder which derives from primary disease) 4)with pleural effusion which need to treat or pericardial effusions 5)with active double cancer 6)pregnant or nursing women or women who like be pregnant 7)with interstitial pneumonitis which is revealed from chest X ray or chest CT 8)with a history of mental disorder or treated it at the moment 9)with sever allergy to docetaxel or S-1, or with a history of sever allergy 10)doctor's decision not to be registered to this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method