Exercise Intervention in Breast Cancer Patients With Treatment-Induced Arthralgia

Not Applicable

Completed

• Conditions: Breast Cancer; Arthralgia
• Interventions: Behavioral: Exercising block

• Registration Number: NCT01236417
• Lead Sponsor: Roswell Park Cancer Institute

Brief Summary

This is a pilot study of a specifically designed exercise intervention developed for breast cancer patients with aromatase-inhibitor related joint pain.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-03
• Study First Submitted: 2010-11-05
• Study First Submitted QC: 2010-11-05
• Study First Posted: 2010-11-07
• Primary Completion: 2012-03
• Status Verified: 2012-04
• Last Update Submitted: 2012-04-12
• Last Update Posted: 2012-04-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 27

Inclusion Criteria

• Post menopausal women with a history of estrogen positive breast cancer who are receiving aromatase inhibitors for at least one month.
• Patients must complain of mild to moderate arthralgia.
• Ability to understand and sign informed consent.
• Patients meet criteria for low to moderate risk for moderate exercise based oon the ACSM guidelines.

Exclusion Criteria

• Inability to comply with study requirements.
• Metastatic breast cancer.
• Patients with orthopedic or neuromuscular disorders that preclude participation in exercise.
• Rheumatoid arthritis.
• History of MI, angina or congestive heart failure.
• Pregnant or lactating females.
• Patients that are high risk for moderate exercise based on ACSM risk classification.
• Patients who exceed minimal physical activity recommendations from the US Surgeon General's Report: Accumulation of 30 minutes or more of moderate physical activity on most days of the week.
• Morbidly obese with BMI ≥ 40

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Exercise	Exercising block	Subjects will be participating in a home-based flexibility and exercise program

Primary Outcome Measures

Name	Time	Method
Effects of exercise	Length of study	To assess the effect of an exercise intervention in breast cancer patients with arthralgia secondary to adjuvant treatment with aromatase inhibitors.

Secondary Outcome Measures

Name	Time	Method
Feasibility of Multi-institutional study	Length of the study	To perform a pilot to access the feasibility of a multi-institutional approach

Trial Locations

Locations (1)

Roswell Park Cancer Institute; 🇺🇸 Buffalo, New York, United States