Effects of Repetitive Electric Sensory Stimulation on Sensorimotor Performance and Pain Intensity in Complex Regional Pain Syndrome Type I
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Complex Regional Pain Syndrome Type I of the Upper Limb
- Sponsor
- Ruhr University of Bochum
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- static tactile 2-point-discrimination threshold
- Last Updated
- 12 years ago
Overview
Brief Summary
The purpose of this study is to test a specific nerve stimulation protocol as therapeutic option in patients diagnosed with CRPS (complex regional pain syndrome) of the upper extremity.
Detailed Description
A specific high frequency electric stimulation is conveyed at 5 days to the affected hand. Each stimulation session lasts 45 minutes.
Investigators
Christoph Maier, Prof. Dr.
Prof. Dr. med Christoph Maier, Head Dep. of Pain Medicine
Ruhr University of Bochum
Eligibility Criteria
Inclusion Criteria
- •Patients diagnosed with CRPS Type I
Exclusion Criteria
- •intolerable hyperalgesia
- •lesions at the fingertips
- •high grade digit contracture
- •central neurologic disorders
- •psychiatric disorders
Outcomes
Primary Outcomes
static tactile 2-point-discrimination threshold
Time Frame: before and after the 5 day stimulation phase with a minimum time of 1h between measurements and start/end of the stimulation (day1 pre and day 5 post)
Thresholds on the tip of the index finger of both hands are assessed using the method of constant stimuli. One single needle and seven pairs of needles with different spacings are tested in randomized order. After each presentation, the subject has to report the sensation of one or two needles by answering immediately "one" or "two." Each distance is presented eight times resulting in 64 single decisions. The summed responses are plotted against distance as a psychometric function for absolute threshold and get fitted by a binary logistic regression. Threshold are taken from the fit at the distance at which 50% correct answers are given.
Secondary Outcomes
- pain intensity(before and after the 5 day stimulation phase with a minimum time of 1h between measurements and start/end of the stimulation (day1 pre and day 5 post))