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Clinical Trials/CTRI/2025/02/080343
CTRI/2025/02/080343Not yet recruitingPhase 2/3

Evaluation of Effectiveness of different photosensitizers used in laser activated disinfection in endodontic infection - An invivo study

Biocare Research Pvt Ltd1 site in 1 country90 target enrollmentStarted: February 23, 2025Last updated:
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Trial Snapshot

Phase
Phase 2/3
Status
Not yet recruiting
Sponsor
Enrollment
90
Locations
1
Primary Endpoint
Postoperative bacterial TVC will be less in photoactivated disinfection group
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

Aim: The aim of this study is to access and compare the disinfection efficacy of different photosensitizers in laser activated disinfection in endodontic infection.

The objective of this study is :

•       To evaluate the decrease in bacterial count after disinfection with Naocl, Photoactivated disinfection with toluidine blue & rose bengal dye

•       To evaluate the clinical outcome & radiographic outcome of cases treated with Naocl, Photoactivated disinfection with toluidine blue & rose bengal dye at 1, 3 and 6 months follow up.

Study Design

Study Type
Interventional
Allocation
Na
Masking
Participant Blinded

Eligibility Criteria

Ages
18.00 Year(s) to 60.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • •Irreversible pulpitis with apical periodontitis Pulpal necrosis Failed root canal therapy.

Exclusion Criteria

  • •Patients with any systemic diseases.
  • •Pregnant patients.
  • •Previously initiated therapy Calcified canals.

Outcomes

Primary Outcomes

Postoperative bacterial TVC will be less in photoactivated disinfection group

Time Frame: Pre & Post operative

Secondary Outcomes

  • periapical healing will be faster in photoactivated disinfection group(3months, 6months)

Investigators

Sponsor
Biocare Research Pvt Ltd
Sponsor Class
Other [Biocare Research Pvt Ltd]
Responsible Party
Principal Investigator
Principal Investigator

Dr Nandina Navya Haritha

Department of Conservative Dentistry and Endodontics

Study Sites (1)

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