Prospective Evaluation of Jugular Vein Thrombi After CPB Cervical Cannulation

Completed

• Conditions: Post-interventional VJI Thrombi After CPB
• Interventions: Procedure: minimally invasive cardiac surgery using a VJI cannula.

• Registration Number: NCT05623670
• Lead Sponsor: Goethe University

Brief Summary

The primary objective of the study is to prospectively analyse the occurrence of post-interventional internal vena jugularis (VJI) thrombi after minimally invasive cardiac surgery using a VJI cannula to perform cardiopulmonary bypass (CPB). The study follows the question whether the performance of a jugular cannulation for the operation under CPB regularly causes wall thromboses despite continuous anticoagulation and a short length of stay of a few hours. The thromboses to be assessed for the study will be obtained by bedside (Doppler) sonography by experienced intensive care physicians in the cardiac surgery intensive care unit. A prospective analysis of all minimal invasive procedures performed with regard to thrombi in the VJI.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-11-12
• Study First Submitted QC: 2022-11-12
• Study First Posted: 2022-11-21
• Study Start: 2022-12-01
• Status Verified: 2024-01
• Primary Completion: 2024-02-01
• Study Completion: 2025-04-01
• Last Update Submitted: 2025-05-05
• Last Update Posted: 2025-05-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

• Minimally invasive cardiac surgery carried out using complete cardiopulmonary bypass.

Exclusion Criteria

• Postoperative support by veno-venous or veno-arterial extracorporeal membrane oxygenation.
• Complications of neck cannula placement or removal.
• Pre-existing occlusion of the vena jugularis interna
• Pre-existing thrombosis of the vena jugularis interna
• Pre-existing prothrombotic coagulation disorder
• Existing catheterisation of the vena jugularis interna within 14 days
• Pre-existing anatomical anomaly of the vena jugularis interna

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients after minimally invasive cardiac surgery using a VJI cannula.	minimally invasive cardiac surgery using a VJI cannula.	-

Primary Outcome Measures

Name	Time	Method
Incidence of post-interventional internal jugular vein thrombi	Detection of thrombi within 24 hours post-intervention	Incidence of post-interventional internal jugular vein thrombi detectable by bedside (doppler) sonography by experienced intensivists in the cardiosurgical intensive care unit.

Trial Locations

Locations (1)

University Hospital Frankfurt; 🇩🇪 Frankfurt, Hessen, Germany