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PRESERVE-Mitral Post-Market Registry or Prospective REgistry to Study Clinical OutcomEs of Repair of Mitral ValvEs in South Asia.

Phase 4
Conditions
Health Condition 1: null- Patients suffering from mitral valve disease and indicated for a mitral valve repair procedure as part of standard care
Registration Number
CTRI/2017/08/009372
Lead Sponsor
Medtronic Plc
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Closed to Recruitment of Participants
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1) Patients with valvular insufficiency and/or stenosis and indicated for the reconstruction and/or remodeling of pathological mitral valves with Profile 3DTM and CG Future annulopasty systems.

2) Indications and contraindications provided in the product Instructions for Use

3) Subject is 18 years of age or older

4) The patient or his/her Legally Authorised Representative ( LAR) has been informed about the nature of the registry and the patient informed consent for study participation has been obtained prior to performing any study-related procedures from the subject or Legally Authorized Representative, as per applicable local requirements.

Exclusion Criteria

1. Contraindications as per IFU:

a. Heavily calcified valves

b. Valvular retraction with severely reduced mobility

c. Active bacterial endocarditis

2. Aortic valve replacement as concomitant procedure

3. Already participating in another clinical study, possibly leading to bias and jeopardizing the scientific appropriate assessment of the study endpoints

Study & Design

Study Type
PMS
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The objective of this registry is to gather data on the clinical outcomes of Medtronic mitral repair products ( Profile 3DTM and CG Future annuloplasty systems) in the approved intended use up to 12 months from the day of procedure.Timepoint: 12 months post procedure
Secondary Outcome Measures
NameTimeMethod
Characterize the demographics of the patients undergoing mitral valve repair using annuloplasty systems in South Asia, and assess the functional and procedural outcomes of the procedure.Timepoint: Discharge, 3-6 months
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