ISRCTN24929928
Completed
Not Applicable
A neuroscience perspective on anxiety proneness - sex differences, monoaminergic pathways and treatment response: a randomised controlled trial
ppsala University (Sweden)0 sites96 target enrollmentAugust 2, 2011
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Social anxiety disorder (social phobia)
- Sponsor
- ppsala University (Sweden)
- Enrollment
- 96
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Social anxiety disorder (social phobia), according to DSM\-IV, must be the main diagnosis as assessed with the structured clinical interview for DSM disorders (SCID)
- •2\. Otherwise somatically healthy
- •3\. Age 18 or older but not postmenopausal
- •4\. Willingness to participate in a symptom provocation brain imaging trial
- •Healthy controls:
- •1\. No psychiatric diagnosis and otherwise somatically healthy
- •2\. Age 18 or older but not postmenopausal
- •3\. Willingness to participate in a brain imaging trial
Exclusion Criteria
- •1\. Treatment of social anxiety within the three months preceding the study
- •2\. Current serious or dominant psychiatric disorder other than social anxiety disorder (e.g. psychosis, major depressive disorder, bipolar disorder)
- •3\. Suicidal ideation
- •4\. Chronic use of prescribed medication that could influence the results
- •5\. Abuse of alcohol or narcotics
- •6\. Pregnancy or planned pregnancy during the study period
- •7\. Menopause
- •8\. Previous positron emission tomography (PET) examination
- •9\. Contraindications for MRI investigations (e.g. implants or other metal objects in the body, brain and heart operations)
Outcomes
Primary Outcomes
Not specified
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