Control of breathing and measurement of disease severity in premature infants with chronic lung disease

Not Applicable

Recruiting

• Conditions: Bronchopulmonary dysplasia; Prematurity; Respiratory - Other respiratory disorders / diseases; Reproductive Health and Childbirth - Complications of newborn

• Registration Number: ACTRN12613000124730
• Lead Sponsor: The Ritchie Centre, Monash University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-02-01
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

Preterm infants < 29 weeks gestation.
1. Healthy preterm infant (<29 weeks) without BPD

Infants with BPD defined as need for oxygen or respiratory support at 36 weeks completed postmenstrual age (PMA).

Infants will be further subdivided into
2. Mild BPD (no need for oxygen or respiratory support at 36 weeks PMA but need for either at 28 days of age).

3. Moderate BPD - need for supplemental oxygen (<30%) at 36 weeks PMA butself-ventilating

4. Severe BPD - need for supplemental oxygen (>30%) at 36 weeks PMA or needing respiratory support.

Infants in Group 1, the healthy preterm infant will be the control group while infants in Groups 2 to 4 with mild/moderate/severe BPD will be in the intervention group

Exclusion Criteria

Infants with congenital heart disease
Infants with major congenital anomalies

Study & Design

• Study Type: Interventional
• Study Design: Not specified