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临床试验/CTRI/2019/04/018540
CTRI/2019/04/018540尚未招募不适用

Comparing Antibacterial Efficacy of Three Rotary System with Different Geometry in Infected Root Canals Before and After Instrumentation – A Double Blinded Randomized Controlled Clinical Trial

riluwan siddique1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2019年12月4日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
Reduction in microbial load was evaluated using real time polymerase chain reaction

研究概览

简要总结

One of the major goals of the treatment of infected root canals of teeth with apical periodontitis is to promote maximal reduction in intracanal bacterial population.ProTaper Next was developed as the successor of the ProTaper Universal system.The Protaper next system was as effective as Protaper Universal and WaveOne in the removal of bacteria during root canal treatment.Recently introduced ProTaper Gold was found to produce less transportation compared to ProTaper Universal . XP-endo Shaper (XP) was introduced in 2015 and boasts of new rotary NiTi snake-shaped instrument developed with MaxWire technology. It has been proved that the XP Endoshaper follows the root canal anatomy of oval shaped canals by preparing and touching more walls than the Vortex Blue system.Till date no study has related to antimicrobial efficacy regarding ProTaper Next,ProTaper Gold and XP Endoshaper in clinical trials. Therefore aim of this randomized controlled clinical trial was to compare the microbial load reduction of  ProTaper Next, ProTaper Gold and XP Endoshaper in infected root canals of teeth with asymptomatic apical periodontitis. The null hypothesis was that there was no statistically significant difference in microbial load reduction between three rotary systems.

研究设计

研究类型
Interventional
分配方式
Permuted block randomization, fixed
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • : asymptomatic apical periodontitis, single & multi-rooted teeth with straight canals, intact pulp chamber walls, necrotic pulps confirmed by pulp tests and, clinical and radiographic evidence of asymptomatic apical periodontitis.

排除标准

  • Teeth with gross carious lesion, crown or root fracture, retreatment, periodontal pocket deeper than 4mm were excluded.

结局指标

主要结局

Reduction in microbial load was evaluated using real time polymerase chain reaction

时间窗: Samples were collected from infected root canals on same day of treatment procedure. No follow up samples collected | Samples collected before instrumentation(S1 samples) | Samples collected after instrumentation (S2 samples)

次要结局

  • Reduction in microbial load was evaluated using real time polymerase chain reaction.(Samples were collected from infected root canals on same day of treatment procedure. No follow up samples collected)

研究者

发起方
riluwan siddique
申办方类型
Other [self]

研究点 (1)

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