Comparing partial pressure of oxygen in Pressure Support Ventilation vs T piece during spontaneous breathing trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 220
- 试验地点
- 1
- 主要终点
- Partial pressure of oxygen level difference pre and post extubation
研究概览
简要总结
The study is single blinded prospective randomised control trial comparing spontaneous breathing trail mode that is pressure support ventilation vs T piece trial mode in adult patients and will be carried out in ICU of Institute of Medical Sciences , Banaras Hindu University, Varanasi. Primary outcome is change in partial pressure of oxygen before and after extubation in T piece mode vs pressure support ventilation mode. Secondary outcome is Comparing atelectasis development after spontaneous breathing trial with pressure support ventilation vs T piece mode. And minimal Oxygen concentration required after extubation to maintain Spo2 of more than 94%.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Adult patient who had received more than 24 hours of mechanical ventilation and met checklist of readiness to start reduction of mechanical ventilation support.
排除标准
- •Refusal for consent Traumatic brain injury or pre-existing neuromuscular disease Patients with do not reintubate order Patient undergone thoracic surgery or with diaphragmatic paralysis.
结局指标
主要结局
Partial pressure of oxygen level difference pre and post extubation
时间窗: Duration of spontaneous breathing trial 30 minutes to 120 minutes | Spo2 more than 94% | Partial pressure oxygen level before spontaneous breath trial then after extubation at 1st hour and 2nd hour
Oxygen requirement post extubation to keep spO2 more than 94%
时间窗: Duration of spontaneous breathing trial 30 minutes to 120 minutes | Spo2 more than 94% | Partial pressure oxygen level before spontaneous breath trial then after extubation at 1st hour and 2nd hour
次要结局
- Reintubation rate(Atelectasis assessment by USG pre & post extubation)
研究者
BHUMIKA THAKUR
INSTITUTE OF MEDICAL SCIENCES , BANARAS HINDU UNIVERSITY