Preoperative Immunonutrition in Patients Undergoing Pelvic Exenteration Surgery for Cancer

Not Applicable

Completed

• Conditions: Cancer; Diet and Nutrition - Other diet and nutrition disorders; Cancer - Other cancer types

• Registration Number: ACTRN12615000308594
• Lead Sponsor: Sophie Lane

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-04-01
• Study Completion: 2018-04-18
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 121

Inclusion Criteria

People who are undergoing pelvic exenteration surgery for cancer

Exclusion Criteria

-People who are under 18
-People who are unable to consent due to language barriers or cognitive function
- People who are unable to consume nutrition supplements 5 days prior to their operation or
- People who are undergoing a pelvic exenteration that is NOT for curative measures

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ength of Stay[Time of discharge from hospital]

Secondary Outcome Measures

Name	Time	Method
umber of complications post operation is the primary outcome For example, Respiratory complications - temperature >37.5 degrees Wound infection - any redness in the area requiring antibiotics Infective diarrhoea - clostridium difficile positive stool culture Septicaemia - positive blood culture treated with antibiotics Anastomotic leak - Any dehiscence with clinical or radiological evidence [3 months post discharge from hospital ];Immune markers and how outcome is assessed - CRP - serum immunoassay, serum albumin - Dye Binding Method, using Cobas and ESR - Westergren Reference Method, Starrsed Analyse[Pre-operation x 2 (pre-operative clinic and the pre-admission clinic), day 3 post operation, day 7 post operation, day 14 post operation and day 21 post operation.]